Boc-Met(O)-Oh

Base Information

• Chemical Name: Boc-Met(O)-Oh
• CAS No.: 34805-21-5
• Molecular Formula: C₁₀H₁₉NO₅S
• Molecular Weight: 265.331
• Hs Code.: 2930 90 98
• DSSTox Substance ID: DTXSID70428575
• Mol file: 34805-21-5.mol

Synonyms:Boc-Met(O)-Oh;34805-21-5;Boc-L-methionine sulfoxide;(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfinylbutanoic acid;(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-methanesulfinylbutanoic acid;Boc-Met(O);boc-met(o)-oh, AldrichCPR;SCHEMBL2998147;DTXSID70428575;FVSDTYGQCVACMH-ISJKBYAMSA-N;MFCD00037172;AKOS015852480;AKOS015897539;AC-8627;AM81987;DS-2367;CS-0154527;N-alpha-t-Butoxycarbonyl-L-methioninesulfoxid;M03309;EN300-6732089;(2S)-2-((tert-Butoxycarbonyl)amino)-4-(methylsulfinyl)butanoic acid;Butanoic acid,2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-(methylsulfinyl)-, (2S)-

Chemical Property of Boc-Met(O)-Oh

Chemical Property:

• Vapor Pressure: 9.48E-12mmHg at 25°C
• Melting Point: 115.6 °C
• Refractive Index: 1.521
• Boiling Point: 509.3 °C at 760 mmHg
• PKA: 3.70±0.10(Predicted)
• Flash Point: 261.8 °C
• PSA: 111.91000
• Density: 1.26 g/cm³
• LogP: 1.98950
• Storage Temp.: Store at RT.
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 265.09839388
• Heavy Atom Count: 17
• Complexity: 310

Purity/Quality:

98%,99%, ^*data from raw suppliers

Boc-L-methionine sulfoxide 99+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NC(CCS(=O)C)C(=O)O
• Isomeric SMILES: CC(C)(C)OC(=O)N[C@@H](CCS(=O)C)C(=O)O

Technology Process of Boc-Met(O)-Oh

There total 2 articles about Boc-Met(O)-Oh which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-tert-butoxycarbonyl-L-methionine (2488-15-5) → Boc-Met(O)-OH (2488-17-7,3913-77-7,57496-45-4,81444-65-7,81444-66-8,81444-67-9,34805-21-5)

Guidance literature:

N-tert-butoxycarbonyl-L-methionine; With dihydrogen peroxide; acetic acid; In water; at 20 ℃; for 0.5h;

With 5%-palladium/activated carbon; In water; at 20 ℃; for 0.5h;

DOI:10.1016/j.tet.2012.06.056

Reference yield:

→ Boc-Met(O)-OH (2488-17-7,3913-77-7,57496-45-4,81444-65-7,81444-66-8,81444-67-9,34805-21-5)

Guidance literature:

L-methionin sulfoxid, t-Buazidoformat;

Reference yield: 100.0%

Boc-Met(O)-OH (2488-17-7,3913-77-7,57496-45-4,81444-65-7,81444-66-8,81444-67-9,34805-21-5) → L-methionine (63-68-3,26062-47-5,58576-49-1)

Guidance literature:

With dimethylsulfide; hydrogen fluoride; at 0 ℃; for 2h; Product distribution;

DOI:10.1016/S0040-4039(00)85621-X

upstream raw materials:

N-tert-butoxycarbonyl-L-methionine

Downstream raw materials:

Boc-Met(O)-Asp(OBzl)-Phe-NH₂

C₁₁₂H₁₄₀Cl₂N₁₄O₂₂S₂

L-methionine

gastrin-5

Refernces