5-benzylamino-2'-deoxyuridine

Base Information

• Chemical Name: 5-benzylamino-2'-deoxyuridine
• CAS No.: 1239968-06-9
• Molecular Formula: C₁₆H₁₉N₃O₅
• Molecular Weight: 333.344
• Mol file: 1239968-06-9.mol

Synonyms:5-benzylamino-2'-deoxyuridine

Chemical Property of 5-benzylamino-2'-deoxyuridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-benzylamino-2'-deoxyuridine

There total 1 articles about 5-benzylamino-2'-deoxyuridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-bromo-2'-deoxyuridine (59-14-3,723-73-9) + benzylamine (100-46-9) → 5-benzylamino-2'-deoxyuridine (1239968-06-9)

Guidance literature:

at 90 ℃; for 3h; Neat (no solvent);

DOI:10.1080/15257770.2010.487507

Reference yield: 100.0%

5-benzylamino-2'-deoxyuridine (1239968-06-9) → 5-amino-2'-deoxyuridine (5536-30-1)

Guidance literature:

With palladium 10% on activated carbon; ammonium formate; In methanol; for 1h; Reflux;

DOI:10.1080/15257770.2010.487507

Reference yield: 81.0%

5-benzylamino-2'-deoxyuridine (1239968-06-9) + tert-butyldimethylsilyl chloride (18162-48-6) → 5'-O-tert-butyldimethylsilyl-5-benzylamino-2'-deoxyuridine

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1016/j.ejmech.2017.06.014

upstream raw materials:

5-bromo-2'-deoxyuridine

benzylamine

Downstream raw materials:

5-amino-2'-deoxyuridine

Refernces

• 1、 Gourdain, Stephanie,Petermann, Christian,Harakat, Dominique,Clivio, Pascale. "Highly efficient and facile synthesis of 5-azido-2'-deoxyuridine". . p. 542 - 546. Retrieved 2010.