N-ACETYL-D-MANNOSAMINE MONOHYDRATE

Base Information

• Chemical Name: N-ACETYL-D-MANNOSAMINE MONOHYDRATE
• CAS No.: 14131-64-7
• Molecular Formula: C8H17NO7
• Molecular Weight: 221.21
• Hs Code.: 29329985
• Mol file: 14131-64-7.mol

Synonyms:

Chemical Property of N-ACETYL-D-MANNOSAMINE MONOHYDRATE

Chemical Property:

• Melting Point: 130 C
• PSA: 128.48000
• LogP: -2.75100

Purity/Quality:

99% ^*data from raw suppliers

N-ACETYL-D-MANNOSAMINE MONOHYDRATE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-ACETYL-D-MANNOSAMINE MONOHYDRATE

There total 138 articles about N-ACETYL-D-MANNOSAMINE MONOHYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(+)-D-glucosamine hydrochloride (1078691-95-8) + acetic anhydride (108-24-7) → N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4)

Guidance literature:

With sodium hydrogencarbonate; In water; at 20 ℃; for 1.5h;

DOI:10.1002/ejoc.200300254

Reference yield:

4-nitrophenyl N-acetyl-β-D-glucosaminide (3459-18-5,50645-66-4) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4)

Guidance literature:

With chitinase from Streptomyces griseus; In phosphate buffer; at 30 ℃; for 1h; pH=6.0; Product distribution; Enzymatic reaction;

DOI:10.1016/S0008-6215(99)00002-6

Reference yield:

acetic acid (64-19-7,77671-22-8) + p-nitrophenyl 2-amino-2-deoxy-β-D-glucopyranosyl-(1->4)-2-acetamido-2-deoxy-β-D-glucopyranoside (219727-01-2) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + N-Acetyl-D-glucosamine (7512-17-6,72-87-7,1136-42-1,1136-44-3,6082-29-7,6730-06-9,7772-94-3,10036-64-3,14131-60-3,14131-64-7,14131-68-1,14215-68-0,62057-49-2,62057-50-5,62057-51-6,62057-52-7,62057-53-8,62057-54-9,62057-55-0,62057-56-1,62075-50-7,62137-54-6,134451-97-1,134522-12-6,148347-16-4)

Guidance literature:

With β-N-acetylhexosaminidase; chitin deacetylase; at 30 ℃; pH=7.0; Further Variations:; reaction time; Product distribution;

DOI:10.1016/S0008-6215(99)00213-X

upstream raw materials:

2-methyl-(1,2-dideoxy-5,6-O-isopropylidene-α-D-glucofurano)-<2,1-d>-2-oxazoline

N-acetyl neuraminic acid

uridine 5'-diphospho-N-acetylglucosamine

methanol

Downstream raw materials:

2-acetamido-2-deoxy-D-glucose

nicotinamide adenine dinucleotide

furfural

methanol

Refernces

• 1、 Cao, L.,Cao, Zh.,Chen, Ch.,Jiang, K.,Liu, Sh.,Liu, W.,Lu, X.,Shao, Zh.,Shi, D.,Su, Z.,Wang, L.,Wang, Y.,Wu, Y.. "Synthesis and Anti-Cholinesterase Activity of Novel Glycosyl Benzofuranylthiazole Derivatives". . p. 1513 - 1518. Retrieved 2021/10/26.
• 2、 Andreeva, Olga V.,Garifullin, Bulat F.,Sharipova, Radmila R.,Strobykina, Irina Yu.,Sapunova, Anastasiya S.,Voloshina, Alexandra D.,Belenok, Mayya G.,Dobrynin, Alexey B.,Khabibulina, Leysan R.,Kataev, Vladimir E.. "Glycosides and Glycoconjugates of the Diterpenoid Isosteviol with a 1,2,3-Triazolyl Moiety: Synthesis and Cytotoxicity Evaluation". . p. 2367 - 2380. Retrieved 2020/08/28.