MAFENIDE ACETATE

Base Information

• Chemical Name: MAFENIDE ACETATE
• CAS No.: 7761-27-5
• Molecular Formula: C9H14N2O4S
• Molecular Weight: 246.28
• Mol file: 7761-27-5.mol

Synonyms:Benzenesulfonamide, 4-(aminomethyl)-, monoacetate;

Chemical Property of MAFENIDE ACETATE

Chemical Property:

Purity/Quality:

95-99% ^*data from raw suppliers

Mafenamideacetate 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Indications: Mafenide (Sulfamylon) is a synthetic antibacterial agent related chemically, but not pharmacologically, to the sulfonamides. The drug appears to interfere with bacterial cellular metabolism and is not antagonized by PABA, pus, or serum. It is bacteriostatic against many gram-positive and gram-negative organisms, including staphylococci, streptococci, and Pseudomonas species. Mafenide is highly soluble and diffuses easily through an eschar. After percutaneous absorption, the drug is metabolized; it acts as a weak carbonic anhydrase inhibitor and may therefore cause systemic acidosis. Mafenide is used primarily in the adjunctive treatment of second- and thirddegree burn wounds. It may cause severe pain on application, and active allergic contact sensitivity may develop.

Technology Process of MAFENIDE ACETATE

There total 1 articles about MAFENIDE ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ mafenide acetate (13009-99-9,7761-27-5)

Guidance literature:

N-Benzyliden-p-aminomethyl-benzolsulfonamid (XVIII), Eg.-W.;

DOI:10.1007/BF00758509