C₁₅H₁₂OS

Base Information

• Chemical Name: C₁₅H₁₂OS
• CAS No.: 137444-54-3
• Molecular Formula: C₁₅H₁₂OS
• Molecular Weight: 240.326
• Mol file: 137444-54-3.mol

Synonyms:C₁₅H₁₂OS

Chemical Property of C₁₅H₁₂OS

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₁₂OS

There total 10 articles about C₁₅H₁₂OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(E)-3-phenylpropenal (14371-10-9) + 2-Acetylthiophene (88-15-3,97511-16-5) → (2E,4E)-5-phenyl-1-(thiophen-2-yl)penta-2,4-dien-1-one (137444-54-3,18594-32-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 5 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.jphotochem.2016.03.009

Reference yield: 83.0%

2-Acetylthiophene (88-15-3,97511-16-5) + 3-phenyl-propenal (104-55-2) → C15H12OS (137444-54-3,18594-32-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 0 - 20 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.organomet.5b00787

Reference yield: 80.0%

allylbenzene (300-57-2,57807-91-7) + 2-(dimethyl(oxo)-λ6-sulfaneylidene)-1-(thiophen-2-yl)ethan-1-one → (2E,4E)-5-phenyl-1-(thiophen-2-yl)penta-2,4-dien-1-one (137444-54-3,18594-32-6)

Guidance literature:

With 2,6-dimethyl-1,4-benzoquinone; palladium diacetate; triphenylphosphine; In dimethyl sulfoxide; at 65 ℃; for 24h; regioselective reaction;

DOI:10.1021/acs.orglett.8b03606

upstream raw materials:

(E)-3-phenylpropenal

2-Acetylthiophene

3-phenyl-propenal

bromobenzene

Downstream raw materials:

(3R,4E)-3-methyl-5-phenyl-1-(thiophen-2-yl)pent-4-en-1-one

C₂₁H₁₆N₂S

C₂₂H₂₂OS

Refernces

• 1、 Yu, Bangkui,Gao, Bao,Zhang, Xuexia,Zhang, Haocheng,Huang, Hanmin. "Palladium-Catalyzed Aminomethylation of Nitrodienes and Dienones via Double C—N Bond Activation". supporting information. p. 566 - 570. Retrieved 2021/02/01.
• 2、 Li, Chunsheng,Li, Meng,Zhong, Wentao,Jin, Yangbin,Li, Jianxiao,Wu, Wanqing,Jiang, Huanfeng. "Palladium-Catalyzed Oxidative Allylation of Sulfoxonium Ylides: Regioselective Synthesis of Conjugated Dienones". . p. 872 - 875. Retrieved 2019/05/16.