Hematoporphyrin monohydrochloride

Base Information

• Chemical Name: Hematoporphyrin monohydrochloride
• CAS No.: 17696-69-4
• Molecular Formula: C34H38 N4 O6 . 2 Cl H
• Molecular Weight: 671.621
• European Community (EC) Number: 241-486-6,241-699-4
• UNII: R9KB28OL6K
• Mol file: 17696-69-4.mol

Synonyms:hematoporphyrin hydrochloride;17471-45-3;Hematoporphyrin monohydrochloride;UNII-R9KB28OL6K;EINECS 241-486-6;R9KB28OL6K;6033-50-7;2,18-Porphinedipropionic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, hydrochloride;21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, hydrochloride;3-[18-(2-carboxyethyl)-8,13-bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid;hydrochloride;17696-69-4;21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, hydrochloride (1:2);7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid hydrochloride;C34H38N4O6.xClH;haematoporphyrin hydrochloride;SCHEMBL1540541;SCHEMBL1540543;APOMKBSOIPKRCP-UHFFFAOYSA-N;C34-H38-N4-O6.x-Cl-H;FT-0696630;21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, monohydrochloride

Chemical Property of Hematoporphyrin monohydrochloride

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 1192.7 ºC at 760 mmHg
• Flash Point: 675.1 ºC
• PSA: 171.36000
• Density: g/cm³
• LogP: 4.24970
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: Insoluble in water. Soluble in pyridine (5%).
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 8
• Exact Mass: 634.2558127
• Heavy Atom Count: 45
• Complexity: 1020

Purity/Quality:

98%,99%, ^*data from raw suppliers

HematoporphyrinDihydrochloride ^*data from reagent suppliers

Safty Information:

• Statements: 33

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C(C)O)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C(C)O.Cl
• Description: Hematoporphyrin is a photosensitizer. Hematoporphyrin (3 μM) increases oxygen consumption and decreases the respiratory control ratio (RCR) in irradiated isolated rat liver mitochondria. It induces DNA breaks in cell-free assays, but not in human HeLa cervical cancer cells, in a light-dependent manner when used at a concentration of 6 μM. Hematoporphyrin (12 μM) decreases the survival of irradiated, but not non-irradiated, HeLa cells. Hematoporphyrin (5 mg/kg) decreases growth of subcutaneous Yoshida AH-130 hepatoma tumors in rats when administered with radiation.
• Uses: Endogenous porphyrin formed by the acid hydrolysis of hemoglobin. It is employed as an active pharmaceutical intermediate.