bis-(1-phenyl-ethylidene)-carbonohydrazide

Base Information

• Chemical Name: bis-(1-phenyl-ethylidene)-carbonohydrazide
• CAS No.: 26323-94-4
• Molecular Formula: C₁₇H₁₈N₄O
• Molecular Weight: 294.356
• Mol file: 26323-94-4.mol

Synonyms:bis-(1-phenyl-ethylidene)-carbonohydrazide

Chemical Property of bis-(1-phenyl-ethylidene)-carbonohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis-(1-phenyl-ethylidene)-carbonohydrazide

There total 4 articles about bis-(1-phenyl-ethylidene)-carbonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

acetophenone p-toluenesulfonylhydrazone (4545-21-5) + potassium carbonate (584-08-7) → bis-(1-phenyl-ethylidene)-carbonohydrazide (26323-94-4)

Guidance literature:

With phosphonic acid diethyl ester; In dimethyl sulfoxide; at 60 ℃; for 10h;

DOI:10.1021/ol500732c

Reference yield:

acetophenone (98-86-2) → bis-(1-phenyl-ethylidene)-carbonohydrazide (26323-94-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / methanol; water / 1 h / Reflux

2: phosphonic acid diethyl ester / dimethyl sulfoxide / 10 h / 60 °C

With hydrogenchloride; phosphonic acid diethyl ester; In methanol; water; dimethyl sulfoxide;

DOI:10.1021/ol500732c

Reference yield:

carbonodihydrazide (497-18-7) + acetophenone (98-86-2) → bis-(1-phenyl-ethylidene)-carbonohydrazide (26323-94-4)

Guidance literature:

With ethanol;

upstream raw materials:

carbonodihydrazide

acetophenone

acetophenone p-toluenesulfonylhydrazone

potassium carbonate

Downstream raw materials:

acetophenonazine

4-aminourazole

Refernces

• 1、 Kothari, Richa,Sharma, Brajraj. "Synthesis, spectroscopic characterization and invitro antimicrobial investigation of some Hg(II) complex of carbohydrazone". experimental part. p. 1577 - 1579. Retrieved 2011/10/18.