Lithium,(4-chlorophenyl)-

Base Information

• Chemical Name: Lithium,(4-chlorophenyl)-
• CAS No.: 14774-78-8
• Molecular Formula: C6H4 Cl Li
• Molecular Weight: 118.492
• Mol file: 14774-78-8.mol

Synonyms:Lithium,(p-chlorophenyl)- (6CI,7CI,8CI); Benzene, chloro-, lithium complex;4-Chlorophenyllithium; p-Chlorophenyllithium

Chemical Property of Lithium,(4-chlorophenyl)-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): 3
• Hazard Codes: 3:
• Safety Statements: Explodes on contact with oxygen. When heated to decomposition it emits tox"> −. See also LITHIUM COMPOUNDS." target="_blank">Explodes on contact with oxygen. When heated to decomposition it emits tox

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Lithium,(4-chlorophenyl)-

There total 9 articles about Lithium,(4-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + diethyl ether (60-29-7,927820-24-4) → 4-chlorophenyl lithium (14774-78-8) + phenyllithium (591-51-5)

Guidance literature:

DOI:10.1021/ja01854a047

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + diethyl ether (60-29-7,927820-24-4) → 4-chlorophenyl lithium (14774-78-8) + phenyllithium (591-51-5)

Guidance literature:

DOI:10.1021/ja01854a047

Reference yield:

bromochlorobenzene (106-39-8) + phenyllithium (591-51-5) → bromobenzene (108-86-1,52753-63-6) + 4-chlorophenyl lithium (14774-78-8)

Guidance literature:

In tetrahydrofuran; biphenyl; pentane; at -75.16 ℃; Equilibrium constant; Inert atmosphere;

DOI:10.1021/jo8020083

upstream raw materials:

bromochlorobenzene

n-butyllithium

diethyl ether

sec.-butyllithium

Downstream raw materials:

2-(4-chloro-phenyl)-7-methyl-quinoline

2-(4-chloro-phenyl)-6-methyl-quinoline

2-(4-chloro-phenyl)-8-methyl-quinoline

4,7-dichloro-2-(4-chlorophenyl)quinoline

Refernces

• 1、 Pietrzak, Marek,Jdrzejewska, Beata. "Synthesis of tetramethylammonium phenyltrialkylborate salts by the addition of alkyllithium reagents to a triorganylborane or organoboranylhalides". experimental part. p. 2135 - 2141. Retrieved 2011/06/20.
• 2、 -. "Pharmaceutically active compounds". Page/Page column 68. . Retrieved 2010/02/13.