1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride

Base Information

• Chemical Name: 1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride
• CAS No.: 49800-23-9
• Molecular Formula: C₁₀H₁₃N*ClH
• Molecular Weight: 183.681
• European Community (EC) Number: 222-397-1,621-523-6
• DSSTox Substance ID: DTXSID60956094
• Mol file: 49800-23-9.mol

Synonyms:1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride;1,2,3,4-Tetrahydronaphthalen-1-amine hydrochloride;49800-23-9;3459-02-7;1,2,3,4-TETRAHYDRO-1-NAPHTHYLAMINE HCL;1,2,3,4-tetrahydronaphthalen-1-amine;hydrochloride;aminotetralin hydrochloride;(METHYLTHIO)ACETICACID;SCHEMBL2481580;DTXSID60956094;DETWFIUAXSWCIK-UHFFFAOYSA-N;MFCD00051984;AKOS015903485;AC-5740;DS-16227;CS-0131597;FT-0606188;FT-0694288;F16883;1,2,3,4-tetrahydro-1-naphthylaminehydrochloride;1,2,3,4-Tetrahydronaphthalen-1-aminehydrochloride;1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride, 98%;Z316170348;1,2,3,4-Tetrahydro-1-naphthalenamine hydrochloride (1:1)

Chemical Property of 1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride

Chemical Property:

• Melting Point: 185-187 °C(lit.)
• Refractive Index: 1.6100 (estimate)
• Boiling Point: 249.6 °C at 760 mmHg
• Flash Point: 110.8 °C
• PSA: 26.02000
• Density: 0.974 g/mL at 25 °C(lit.)
• LogP: 3.52500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 183.0814771
• Heavy Atom Count: 12
• Complexity: 133

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

Useful:

• Canonical SMILES: C1CC(C2=CC=CC=C2C1)N.Cl
• Uses: 1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride was used in enantiomeric separation using β-cyclodextrin-bonded negatively charged polyacrylamide gel-filled capillaries.

Technology Process of 1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride

There total 1 articles about 1,2,3,4-Tetrahydro-1-naphthylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

tetralin (119-64-2) → 1,2,3,4-tetrahydro-1-naphthylamine hydrochloride (3459-02-7,49800-23-9,32908-42-2)

Guidance literature:

tetralin; With Benzophenone imine; copper(l) iodide; 1,10-Phenanthroline; di-tert-butyl peroxide; In chlorobenzene; at 90 ℃; for 48h; Inert atmosphere; Sealed tube;

With hydrogenchloride; In methanol; water; chlorobenzene; at 40 ℃; for 15h; regioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.8b03505

upstream raw materials:

tetralin

Refernces