1,2-Bis(4-chlorophenyl)hydrazine

Base Information

• Chemical Name: 1,2-Bis(4-chlorophenyl)hydrazine
• CAS No.: 953-14-0
• Molecular Formula: C12H10 Cl2 N2
• Molecular Weight: 253.131
• Hs Code.: 2928000090
• NSC Number: 86541
• DSSTox Substance ID: DTXSID60292944
• Nikkaji Number: J80.040F
• Wikidata: Q82031461
• Mol file: 953-14-0.mol

Synonyms:1,2-bis(4-chlorophenyl)hydrazine;953-14-0;N,N'-Bis-(4-chloro-phenyl)-hydrazine;N,N'-Bis-(4-chlorophenyl)hydrazine;4,4'-dichlorohydrazobenzene;NSC86541;NCIOpen2_004824;SCHEMBL3260825;DTXSID60292944;BVPHWSDABGXRQD-UHFFFAOYSA-N;1,2-bis(4-chlorophenyl)-hydrazine;MFCD19441853;NSC-86541;N,N-Bis-(4-chloro-phenyl)-hydrazine;AS-47834;CS-0208941;F16325;J-523215

Chemical Property of 1,2-Bis(4-chlorophenyl)hydrazine

Chemical Property:

• Vapor Pressure: 0.00232mmHg at 25°C
• Boiling Point: 288.6°Cat760mmHg
• Flash Point: 128.3°C
• PSA: 24.06000
• Density: 1.405g/cm³
• LogP: 4.57840
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 252.0221037
• Heavy Atom Count: 16
• Complexity: 175

Purity/Quality:

99% ^*data from raw suppliers

1,2-Bis(4-chlorophenyl)hydrazine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1NNC2=CC=C(C=C2)Cl)Cl

Technology Process of 1,2-Bis(4-chlorophenyl)hydrazine

There total 17 articles about 1,2-Bis(4-chlorophenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-chlorobenzonitrile (100-00-5) → 4-chloro-aniline (106-47-8) + N,N'-bis(4-chlorophenyl)hydrazine (953-14-0)

Guidance literature:

With 1,1,3,3-Tetramethyldisiloxane; In ethanol; at 20 ℃; Reagent/catalyst; chemoselective reaction; Kinetics;

DOI:10.1021/cs500379u

Reference yield: 98.0%

bis-(4-chloro-phenyl)-diazene (1602-00-2) → N,N'-bis(4-chlorophenyl)hydrazine (953-14-0)

Guidance literature:

With ammonium chloride; zinc; In water; acetone;

DOI:10.1021/ja00265a026

Reference yield: 96.0%

4,4'-bis(chloro)azoxybenzene (614-26-6) → N,N'-bis(4-chlorophenyl)hydrazine (953-14-0)

Guidance literature:

With sodium dithionite; 1,1′-dioctyl-4,4′-bipyridinium; potassium carbonate; In water; acetonitrile; at 35 ℃; for 2h;

DOI:10.1016/S0040-4039(96)01451-7

upstream raw materials:

4-chlorobenzonitrile

4,4'-bis(chloro)azoxybenzene

bis-(4-chloro-phenyl)-diazene

(E)-bis(4-chlorophenyl)diazene

Downstream raw materials:

1-acetyl-1,2-bis(4-chlorphenyl)hydrazine

N,N'-diacetyl-N,N'-di(4-chlorophenyl)hydrazine

1,2-bis(4-chlorophenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

N-(4-chlorophenyl)-2,2,2-trifluoroacetamide

Refernces

• 1、 Sahoo, Manoj K.,Sivakumar, Ganesan,Jadhav, Sanjay,Shaikh, Samrin,Balaraman, Ekambaram. "Convenient semihydrogenation of azoarenes to hydrazoarenes using H2". supporting information. p. 5289 - 5293. Retrieved 2021/06/30.
• 2、 Du, Wanting,Ma, Zichao,Shao, Liming,Wang, Jian. "Hydrogen peroxide based oxidation of hydrazines using HBr catalyst". . . Retrieved 2021/11/18.