3-nitrophenyl methane sulfonate

Base Information

• Chemical Name: 3-nitrophenyl methane sulfonate
• CAS No.: 19013-29-7
• Molecular Formula: C₇H₇NO₅S
• Molecular Weight: 217.202
• Mol file: 19013-29-7.mol

Synonyms:3-nitrophenyl methane sulfonate

Chemical Property of 3-nitrophenyl methane sulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-nitrophenyl methane sulfonate

There total 5 articles about 3-nitrophenyl methane sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methanesulfonic acid (75-75-2,98527-29-8) + 3-nitrophenyl acetate (1523-06-4) → 3-nitrophenyl methane sulfonate (19013-29-7)

Guidance literature:

With trichlorophosphate; at 100 ℃; for 6h;

DOI:10.1016/S0040-4020(99)00759-0

Reference yield: 90.0%

methanesulfonic acid (75-75-2,98527-29-8) + 3-nitrophenyl benzoate (1523-13-3) → 3-nitrophenyl methane sulfonate (19013-29-7)

Guidance literature:

With trichlorophosphate; at 100 ℃; for 6h;

DOI:10.1016/S0040-4020(99)00759-0

Reference yield: 63.0%

methanesulfonic acid (75-75-2,98527-29-8) + 3-nitrobenzenediazonium o-benzenedisulfonimide → 3-nitrophenyl methane sulfonate (19013-29-7)

Guidance literature:

at 120 ℃; for 2.5h;

DOI:10.1055/s-1999-3696

upstream raw materials:

meta-nitrophenol

methanesulfonyl chloride

methanesulfonic acid

3-nitrophenyl acetate

Downstream raw materials:

3-nitrophenolate anion

3-((4-((4-(3-(3-(tert-butyl)-1-(6-methoxypyridin-3-yl)-1H-pyrazol-5-yl)ureido)naphthalen-1-yl)oxy)pyrimidin-2-yl)amino)phenyl methanesulfonate

3-aminophenyl methanesulfonate

3-((4-((4-(3-(3-isopropyl-1-(p-tolyl)-1H-pyrazol-5-yl)ureido)naphthalen-1-yl)oxy)pyrimidin-2-yl)amino)phenyl methanesulfonate

Refernces

• 1、 B?rgel, Jonas,Tanwar, Lalita,Berger, Florian,Ritter, Tobias. "Late-Stage Aromatic C-H Oxygenation". supporting information. p. 16026 - 16031. Retrieved 2018/12/13.
• 2、 -. "A method of hydroxylation org. compd. sulfonylated". Page 22. . Retrieved 2010/02/14.