(R)-Cyano(phenyl)methyl acetate

Base Information Edit

Chemical Name:(R)-Cyano(phenyl)methyl acetate
CAS No.:119718-89-7
Molecular Formula:C10H9 N O2
Molecular Weight:175.187
Hs Code.:2926909090
European Community (EC) Number:621-297-9
DSSTox Substance ID:DTXSID70452951
Nikkaji Number:J828.302H
Wikidata:Q76416518
Mol file:119718-89-7.mol

Synonyms:119718-89-7;(R)-Cyano(phenyl)methyl acetate;[(R)-cyano(phenyl)methyl] acetate;(R)-alpha-Cyanobenzyl acetate;Benzeneacetonitrile, alpha-(acetyloxy)-, (alphaR)-;O-Acetyl-D-mandelonitrile;(R)-alpha-Acetoxyphenylacetonitrile;(R)-(+)-ALPHA-ACETOXYPHENYLACETONITRILE;r(-)-O-acetylmandelonitrile;(R)-Acetoxyphenylacetonitrile;(R)-a-acetoxyphenylacetonitrile;DTXSID70452951;(R)- alpha -Acetoxyphenylacetonitrile;AKOS015913202;J-004183;(R)-alpha-Acetoxyphenylacetonitrile, >=97.0% (sum of enantiomers, GC)

Suppliers and Price of (R)-Cyano(phenyl)methyl acetate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chem-Impex
(R)-α-Acetoxyphenylacetonitrile,97%(Chiralpurity) 97%(Chiralpurity)
1ML
$ 183.68

American Custom Chemicals Corporation
(R)-(+)-ALPHA-ACETOXYPHENYLACETONITRILE 95.00%
5MG
$ 501.84

Total 10 raw suppliers

Chemical Property of (R)-Cyano(phenyl)methyl acetate Edit

Chemical Property:

Vapor Pressure:0.006mmHg at 25°C
Refractive Index:n20/D 1.506
Boiling Point:274°Cat760mmHg
Flash Point:123.8°C
PSA：50.09000
Density:1.145g/cm³
LogP:1.81438
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:175.063328530
Heavy Atom Count:13
Complexity:222

Purity/Quality:

99% ^*data from raw suppliers

(R)-α-Acetoxyphenylacetonitrile,97%(Chiralpurity) 97%(Chiralpurity) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC(C#N)C1=CC=CC=C1
Isomeric SMILES:CC(=O)O[C@@H](C#N)C1=CC=CC=C1
Uses (R)-α-Acetoxyphenylacetonitrile can be used as a model compound in the iodine promoted as well as t-BuONO-assisted secondary amides synthesis via an aryl?N-addition reaction to the -CN group of nitriles.

Technology Process of (R)-Cyano(phenyl)methyl acetate

There total 81 articles about (R)-Cyano(phenyl)methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 7677-24-9
trimethylsilyl cyanide

: 108-24-7
acetic anhydride

: 100-52-7
benzaldehyde

: 119718-87-5,119718-88-6,119718-89-7,5762-35-6,72690-96-1
cyano(phenyl)methyl acetate

Guidance literature:: trimethylsilyl cyanide; benzaldehyde; at 20 ℃; for 12h; Ionic liquid;

acetic anhydride; at 20 ℃; for 12h;
DOI:10.1080/00397910802431172

Reference yield: 99.0%

: 25438-37-3
phenyl(trimethylsiloxy)acetonitrile

: 108-24-7
acetic anhydride

: 119718-87-5,119718-88-6,119718-89-7,5762-35-6,72690-96-1
cyano(phenyl)methyl acetate

Guidance literature:: With polymeric supported 1-(3-sulfonatopropyl)-1H-imidazol-3-ium trifluoromethanesulfonate scandium(II); at 40 ℃; for 24h; Flow reactor;
DOI:10.1002/cctc.201900086