1-Bromo-3-chloro-5-iodobenzene

Base Information

• Chemical Name: 1-Bromo-3-chloro-5-iodobenzene
• CAS No.: 13101-40-1
• Molecular Formula: C6H3BrClI
• Molecular Weight: 317.351
• Hs Code.: 2903998090
• Mol file: 13101-40-1.mol

Synonyms:1-BROMO-3-CHLORO-5-IODOBENZENE

Chemical Property of 1-Bromo-3-chloro-5-iodobenzene

Chemical Property:

• Vapor Pressure: 0.00644mmHg at 25°C
• Melting Point: 85.8℃
• Refractive Index: 1.663
• Boiling Point: 280.408 °C at 760 mmHg
• Flash Point: 123.386 °C
• PSA: 0.00000
• Density: 2.273 g/cm³
• LogP: 3.70710
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

1-Bromo-3-chloro-5-iodobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Bromo-3-chloro-5-iodobenzene

There total 10 articles about 1-Bromo-3-chloro-5-iodobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1,3-dibromo-5-chlorobenzene (14862-52-3) → 1-bromo-3-chloro-5-iodobenzene (13101-40-1)

Guidance literature:

1,3-dibromo-5-chlorobenzene; With isopropylmagnesium chloride; at -25 ℃; for 16h; Inert atmosphere;

With iodine; at 20 ℃; for 17h; Inert atmosphere;

Reference yield:

2-bromo-6-chloro-4-iodoaniline (873386-83-5) → 1-bromo-3-chloro-5-iodobenzene (13101-40-1)

Guidance literature:

With phosphinic acid; sodium nitrite; In ethanol; at 20 - 25 ℃; for 3h;

Reference yield:

2-(3-bromo-5-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (488850-91-5) → 1-bromo-3-chloro-5-iodobenzene (13101-40-1)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; potassium iodide; In methanol; water; at 80 ℃; for 1h; High pressure;

DOI:10.1021/ol303164h

upstream raw materials:

3-bromo-5-chlorophenylamine

2-bromo-4-chloro-6-iodoaniline

4-chloro-2-bromoaniline

1-bromo-3-chlorobenzene

Downstream raw materials:

2-(3-bromo-5-chlorophenyl )-4,6-diphenyl-1,3,5-triazine

Refernces

• 1、 -. "A 1-chloro-3-bromo-5-iodophenylamino preparation method". Paragraph 0017. . Retrieved 2016/12/01.