N,N'-Di-p-tolylbenzidine

Base Information

• Chemical Name: N,N'-Di-p-tolylbenzidine
• CAS No.: 10311-61-2
• Molecular Formula: C26H24N2
• Molecular Weight: 364.49
• Hs Code.: 2921590090
• DSSTox Substance ID: DTXSID80596870
• Wikidata: Q72471213
• Mol file: 10311-61-2.mol

Synonyms:10311-61-2;N,N'-Di-p-tolylbenzidine;N4,N4'-Di-p-tolyl-[1,1'-biphenyl]-4,4'-diamine;N,N'-Bis(4-methylphenyl)benzidine;N,N'-Di-(4-methyl-phenyl)-benzidine;4-methyl-N-[4-[4-(4-methylanilino)phenyl]phenyl]aniline;MFCD09833311;N,N'-Di-(4-methylphenyl)benzidine;[1,1'-Biphenyl]-4,4'-diamine, N,N'-bis(4-methylphenyl)-;N,N\'-Di-p-tolylbenzidine;SCHEMBL1921510;DTXSID80596870;AKOS015901856;CS-W011815;DS-6639;SB66595;N,N/'-Di-(4-methyl-phenyl)-benzidine;AC-28769;SY037127;DB-058921;D3567;F15211;A855250;N,N inverted exclamation mark -Di-p-tolylbenzidine;N~4~,N~4'~-Bis(4-methylphenyl)[1,1'-biphenyl]-4,4'-diamine;N4,N4'-BIS(4-METHYLPHENYL)-[1,1'-BIPHENYL]-4,4'-DIAMINE;N-(4-METHYLPHENYL)-4-{4-[(4-METHYLPHENYL)AMINO]PHENYL}ANILINE

Chemical Property of N,N'-Di-p-tolylbenzidine

Chemical Property:

• Melting Point: 240 °C
• Boiling Point: 562.5 °C at 760 mmHg
• PKA: 1.83±0.50(Predicted)
• Flash Point: 355.6 °C
• PSA: 24.06000
• Density: 1.141 g/cm³
• LogP: 7.60360
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 7.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 364.193948774
• Heavy Atom Count: 28
• Complexity: 389

Purity/Quality:

99%, ^*data from raw suppliers

N,N''-Di-p-tolylbenzidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)NC2=CC=C(C=C2)C3=CC=C(C=C3)NC4=CC=C(C=C4)C

Technology Process of N,N'-Di-p-tolylbenzidine

There total 6 articles about N,N'-Di-p-tolylbenzidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-methyldiphenylamine (620-84-8) → N4,N4'-di-p-tolyl-[1,1'-biphenyl]-4,4'-diamine (10311-61-2)

Guidance literature:

4-methyldiphenylamine; With methanesulfonic acid; In dichloromethane; at 0 ℃;

With chloranil; In dichloromethane; at 0 - 20 ℃; for 0.5h;

DOI:10.1021/acs.joc.7b01377

Reference yield: 74.0%

4,4'-diiodobiphenyl (3001-15-8) + p-toluidine (106-49-0,12221-03-3) → N4,N4'-di-p-tolyl-[1,1'-biphenyl]-4,4'-diamine (10311-61-2)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri-tert-butyl phosphine; sodium t-butanolate; In toluene; for 15h; Inert atmosphere; Reflux;

DOI:10.1021/acs.organomet.8b00013

Reference yield:

Triphenylsilyl chloride (76-86-8) → N4,N4'-di-p-tolyl-[1,1'-biphenyl]-4,4'-diamine (10311-61-2)

Guidance literature:

With n-butyllithium; In hexane;

upstream raw materials:

4-methyldiphenylamine

sulfuric acid

acetic acid

Triphenylsilyl chloride

Downstream raw materials:

C₅₈H₄₀N₂

N,N'-dinitroso-N,N'-di-p-tolyl-benzidine

Refernces

• 1、 Maddala, Sudhakar,Mallick, Sudesh,Venkatakrishnan, Parthasarathy. "Metal-Free Oxidative C-C Coupling of Arylamines Using a Quinone-Based Organic Oxidant". . p. 8958 - 8972. Retrieved 2017/09/11.
• 2、 -. "Silanamine derivative and process for the production thereof, and organical EL device using the said silanamine derivative". . . Retrieved 2008/06/13.