dl-Alanyl-dl-leucine

Base Information

• Chemical Name: dl-Alanyl-dl-leucine
• CAS No.: 1999-42-4
• Molecular Formula: C₉H₁₈N₂O₃
• Molecular Weight: 202.254
• NSC Number: 89666,89664,89609
• DSSTox Substance ID: DTXSID80936873
• Wikidata: Q82913082
• ChEMBL ID: CHEMBL1221716
• Mol file: 1999-42-4.mol

Synonyms:dl-Alanyl-dl-leucine;1999-42-4;2-(2-aminopropanamido)-4-methylpentanoic acid;2-(2-aminopropanoylamino)-4-methylpentanoic acid;1638-60-4;DL-Ala-DL-Leu;MFCD00025555;H-DL-Ala-Leu-OH;(2S)-2-[[(2R)-2-aminopropanoyl]amino]-4-methylpentanoic acid;(2S)-2-(2-aminopropanoylamino)-4-methylpentanoic acid;alanyl-DL-leucine;2-(2-azanylpropanoylamino)-4-methyl-pentanoic acid;2-[(2-amino-1-oxopropyl)amino]-4-methylpentanoic acid;NSC89609;DL-Alanine-DL-leucine;H-DL-Ala-DL-Leu-OH;SCHEMBL1171451;N-(2-Aminopropanoyl)leucine #;CHEMBL1221716;DTXSID80936873;CHEBI:177395;BAA99942;NSC89664;NSC89666;NSC-89609;NSC-89664;NSC-89666;AKOS009158119;CCG-233356;CS-W015502;HY-W014786;N-(2-Amino-1-hydroxypropylidene)leucine;BS-44084;A0185;FT-0633725;FT-0633966;FT-0634765;FT-0641102;FT-0695788;2-(2-aminopropanamido)-4-methylpentanoicacid;D88225;2-(2-aminopropanoylamino)-4-methyl-pentanoic acid;A810521;A821575;A835633;L012879;BRD-A08636822-001-01-4

Chemical Property of dl-Alanyl-dl-leucine

Chemical Property:

• Boiling Point: 409.7 °C at 760 mmHg
• PKA: 3.16±0.10(Predicted)
• Flash Point: 201.6 °C
• PSA: 92.42000
• Density: 1.108 g/cm³
• LogP: 1.04030
• Storage Temp.: −20°C
• XLogP3: -2.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 202.13174244
• Heavy Atom Count: 14
• Complexity: 216

Purity/Quality:

99% ^*data from raw suppliers

DL-Alanyl-DL-leucine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC(C(=O)O)NC(=O)C(C)N

Technology Process of dl-Alanyl-dl-leucine

There total 6 articles about dl-Alanyl-dl-leucine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-bromo-propionyl)-leucine (6491-32-3) → D,L-alanyl-D,L-leucine (1999-42-4,6491-39-0)

Guidance literature:

With ammonia; water; at 100 ℃; inactive alanyl-leucine B, whose phenylcarbamoyl derivative by/at 185-189 degree is melting;

Reference yield:

LEUCINE (328-39-2,21675-61-6,25248-98-0,70-45-1) → D,L-alanyl-D,L-leucine (1999-42-4,6491-39-0)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH-solution / man trennt durch fraktionierte Krystallisation aus Wasser

2: water; ammonia / 100 °C

With sodium hydroxide; ammonia; water;

Reference yield:

N-Formyl-DL-alanyl-DL-leucin (99977-23-8) → D,L-alanyl-D,L-leucine (1999-42-4,6491-39-0)

Guidance literature:

With dihydrogen peroxide;

upstream raw materials:

N-(2-bromo-propionyl)-leucine

N-Formyl-DL-alanyl-DL-leucin

N-[N-(toluene-4-sulfonyl)-alanyl]-leucine

hydrogen iodide

Downstream raw materials:

DL-alanyl-leucyl anhydride

LEUCINE

glycyl=>alanyl=>leucine