Trans-4-Chloro-2-Buten-1-ol

Base Information

• Chemical Name: Trans-4-Chloro-2-Buten-1-ol
• CAS No.: 1775-39-9
• Molecular Formula: C4H7ClO
• Molecular Weight: 106.552
• Hs Code.: 2905590090
• Mol file: 1775-39-9.mol

Synonyms:trans-4-Chloro-2-buten-1-ol;(E)-1-Chloro-4-hydroxy-2-butene;(E)-4-Chloro-2-buten-1-ol;2-Buten-1-ol,4-chloro-, (E)- (8CI);(E)-1-Chloro-2-buten-4-ol;

Chemical Property of Trans-4-Chloro-2-Buten-1-ol

Chemical Property:

• Boiling Point: 182.78 °C at 760 mmHg
• Flash Point: 83.22 °C
• PSA: 20.23000
• Density: 1.098 g/cm³
• LogP: 0.77370

Purity/Quality:

99% ^*data from raw suppliers

(E)-4-CHLOROBUT-2-EN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Trans-4-Chloro-2-Buten-1-ol

There total 1 articles about Trans-4-Chloro-2-Buten-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-butenediol (821-11-4,6117-80-2,110-64-5) → (Z)-4-chloro-but-2-en-1-ol (1576-93-8) + 1-chloro-4-hydroxy-2-butene (1775-39-9)

Guidance literature:

With pyridine; thionyl chloride; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1007/BF00962333

Reference yield: 75.0%

1-chloro-4-hydroxy-2-butene (1775-39-9) + p-toluenesulfonyl chloride (98-59-9) → (E)-1-chloro-4-tosyloxy-2-butene

Guidance literature:

With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; at 0 ℃; for 4h;

DOI:10.1002/jlcr.1412

Reference yield:

chloro-trimethyl-silane (75-77-4) + 1-chloro-4-hydroxy-2-butene (1775-39-9) → (Z)-4-chloro-but-2-en-1-ol (1576-93-8) + trans-4-(trimethylsiloxy)-2-butenyl chloride (86943-30-8)

Guidance literature:

With triethylamine; In diethyl ether; for 2h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00169a003

upstream raw materials:

1,4-butenediol

Downstream raw materials:

(3-Chloro-phenyl)-carbamic acid (E)-4-chloro-but-2-enyl ester

(Z)-4-chloro-but-2-en-1-ol

trans-4-(trimethylsiloxy)-2-butenyl chloride

diphenyl<(E)-4-hydroxy-2-buten-1-yl>phosphine oxide

Refernces