4'-O-benzoyl digitoxin

Base Information

• Chemical Name: 4'-O-benzoyl digitoxin
• CAS No.: 1250858-27-5
• Molecular Formula: C₄₈H₆₈O₁₄
• Molecular Weight: 869.06
• Mol file: 1250858-27-5.mol

Synonyms:4'-O-benzoyl digitoxin

Chemical Property of 4'-O-benzoyl digitoxin

Chemical Property:

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Technology Process of 4'-O-benzoyl digitoxin

There total 1 articles about 4'-O-benzoyl digitoxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

benzoic acid anhydride (93-97-0) + digitoxin (71-63-6) → 4'-O-benzoyl digitoxin (1250858-27-5)

Guidance literature:

digitoxin; With 2,4,6-trimethyl-pyridine; (2S,5S)-2,5-bis[[(2S)-3-(1H-indol-3-yl)-1-(octyloxy)-1-oxopropan-2-ylamino]carbonyl]-1-(pyridin-4-yl)pyrrolidine; In chloroform; at 20 ℃; for 0.166667h;

benzoic acid anhydride; In chloroform; at 20 ℃; for 24h; regioselective reaction;

DOI:10.1016/j.tetlet.2010.07.036

upstream raw materials:

benzoic acid anhydride

digitoxin

Refernces