Ethyl picolinimidate

Base Information

• Chemical Name: Ethyl picolinimidate
• CAS No.: 41050-95-7
• Molecular Formula: C8H10 N2 O
• Molecular Weight: 150.18
• Hs Code.: 2933399090
• European Community (EC) Number: 809-961-8
• DSSTox Substance ID: DTXSID30483044
• Nikkaji Number: J1.575.602K
• Wikidata: Q82320003
• Mol file: 41050-95-7.mol

Synonyms:Ethyl picolinimidate;41050-95-7;PYRIDINE-2-CARBOXIMIDIC ACID ETHYL ESTER;ETHYL PYRIDINE-2-CARBOXIMIDATE;2-Pyridinecarboximidic acid, ethyl ester;SCHEMBL504660;ethoxy-pyridin-2-ylmethanimine;DTXSID30483044;REFQUZRLOKSTFL-UHFFFAOYSA-N;AKOS010211569;SB54564;PYRIDINE-2-CARBOXIMIDICACIDETHYLESTER;CS-0361628;F18164

Chemical Property of Ethyl picolinimidate

Chemical Property:

• PSA: 45.97000
• LogP: 1.54320
• Storage Temp.: 2-8°C
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 150.079312947
• Heavy Atom Count: 11
• Complexity: 136

Purity/Quality:

99% ^*data from raw suppliers

pyridine-2-carboximidicacidethylester 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=N)C1=CC=CC=N1

Technology Process of Ethyl picolinimidate

There total 5 articles about Ethyl picolinimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-Cyanopyridine (100-70-9,1232006-36-8) + ethanol (64-17-5) → ethyl picolinimidate (41050-95-7)

Guidance literature:

With sodium; at 21 - 24 ℃; for 12h;

DOI:10.1002/anie.202010840

Reference yield: 93.0%

2-Cyanopyridine (100-70-9,1232006-36-8) + sodium ethanolate (141-52-6) → ethyl picolinimidate (41050-95-7)

Guidance literature:

In ethanol;

Reference yield:

pyridine-3-carbonitrile (100-54-9,121697-66-3,1232169-17-3,68271-95-4) + ethanol (64-17-5) → ethyl picolinimidate (41050-95-7)

Guidance literature:

pyridine-3-carbonitrile; ethanol; With hydrogenchloride;

With sodium hydroxide; In water;

DOI:10.1107/S205322961800284X

upstream raw materials:

2-Cyanopyridine

sodium ethanolate

ethanol

pyridine-2-carboxylic acid amide

Downstream raw materials:

2-[4,5-dihydro-1,3-oxazol-2-yl]pyridine

4,4-dimethyl-2-(pyridin-2-yl)-2-oxazoline

Ph-pyridyloxazoline

isopropyl-pyridyloxazoline

Refernces

• 1、 Deng, Ruohan,Engle, Keary M.,Fu, Yue,Gao, Yang,Li, Zi-Qi,Liu, Peng,Tran, Van T.. "Ligand-Controlled Regiodivergence in Nickel-Catalyzed Hydroarylation and Hydroalkenylation of Alkenyl Carboxylic Acids**". supporting information. p. 23306 - 23312. Retrieved 2020/10/19.
• 2、 -. "MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF". Page/Page column 163-164. . Retrieved 2008/12/07.