heptyl 4-nitrobenzoate

Base Information

• Chemical Name: heptyl 4-nitrobenzoate
• CAS No.: 14309-44-5
• Molecular Formula: C₁₄H₁₉NO₄
• Molecular Weight: 265.309
• Mol file: 14309-44-5.mol

Synonyms:heptyl 4-nitrobenzoate

Chemical Property of heptyl 4-nitrobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of heptyl 4-nitrobenzoate

There total 6 articles about heptyl 4-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

n-heptan1ol (111-70-6) + 4-nitro-benzoic acid (62-23-7) → heptyl 4-nitrobenzoate (14309-44-5)

Guidance literature:

With Candida antarctica lipase B immobilised in a macroporous DVB crosslinked polymer (Novozym 435); In cyclohexane; at 80 ℃; for 24h; Enzymatic reaction;

DOI:10.1016/j.tetlet.2013.07.065

Reference yield: 83.0%

1-Bromoheptane (629-04-9) + 4-nitrobenzaldehdye (555-16-8) → heptyl 4-nitrobenzoate (14309-44-5)

Guidance literature:

With oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,3-bis(mesityl)imidazolium chloride; In tetrahydrofuran; at 50 ℃; for 24h; under 760.051 Torr;

DOI:10.1002/ejoc.201100937

Reference yield: 76.0%

4-nitrobenzyl chloride (619-73-8) + 1-Bromoheptane (629-04-9) → 4'-(nitrobenzyl) 4-nitrobenzoate (3481-11-6) + heptyl 4-nitrobenzoate (14309-44-5)

Guidance literature:

With manganese(IV) oxide; oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,3-bis(mesityl)imidazolium chloride; In tetrahydrofuran; at 50 ℃; for 24h;

DOI:10.1002/ejoc.201100937

upstream raw materials:

n-heptan1ol

4-nitro-benzoyl chloride

4-nitro-benzoic acid

4-nitrobenzyl chloride

Downstream raw materials:

n-heptyl p-aminobenzoate

Refernces

• 1、 Giunta, Daniela,Masia, Maria Paola,Marchetti, Mauro,Morrone, Raffaele,Solinas, Maurizio. "Immobilised Candida antarctica B as efficient catalyst for the synthesis of local anaesthetic intermediates". supporting information. p. 5122 - 5125. Retrieved 2013/08/28.
• 2、 Matsunaga, Y.,Sakamoto S.,Togashi, A.,Tsujimoto, M.. "Smectogenic Salts Formed by Combination of Alkyl p-Aminobenzoates and p-Ethyl- or p-Chlorobenzenesulfonic Acid". . p. 161 - 166. Retrieved 2007/10/02.