1,1,1,2-Tetrafluoropropane

Base Information

• Chemical Name: 1,1,1,2-Tetrafluoropropane
• CAS No.: 421-48-7
• Molecular Formula: C3H4 F4
• Molecular Weight: 116.058
• Hs Code.: 2903399090
• European Community (EC) Number: 829-059-8
• DSSTox Substance ID: DTXSID90503373
• Nikkaji Number: J666.240D
• Mol file: 421-48-7.mol

Synonyms:1,1,1,2-tetrafluoropropane;421-48-7;Propane, 1,1,1,2-tetrafluoro-;tetrafluoropropane;SCHEMBL24871;DTXSID90503373;PKLPRWBVQPHGTR-UHFFFAOYSA-N;AKOS006345301

Chemical Property of 1,1,1,2-Tetrafluoropropane

Chemical Property:

• Vapor Pressure: 2540mmHg at 25°C
• Refractive Index: 1.261
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: 1.157g/cm³
• LogP: 1.90670
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 116.02491278
• Heavy Atom Count: 7
• Complexity: 54.4

Purity/Quality:

98%min ^*data from raw suppliers

1,1,1,2-Tetrafluoropropane 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(F)(F)F)F

Technology Process of 1,1,1,2-Tetrafluoropropane

There total 18 articles about 1,1,1,2-Tetrafluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.6%

Methyl fluoride (593-53-3) + 1,1,2-trifluoroethylene (359-11-5) → 1,1,1,2-tetrafluoroethane (811-97-2) + 1,1,1,2-tetrafluoropropane (421-48-7)

Guidance literature:

With antimony pentafluoride; at 25 ℃; for 14h;

DOI:10.1016/S0022-1139(00)00408-5

Reference yield:

2,2-dichloro-1,1,1,3,3,3-hexafluoro-propane (1652-80-8) + 1,2-dichlorohexafluoropropane (661-97-2) → 1,1,1,2,3,3,3-Heptafluoropropane (431-89-0) + perfluoropropylene (116-15-4,13429-24-8,25120-07-4,6792-31-0) + 1,1,1,2,2,3-hexafluoropropane (677-56-5) + 1,1,1,2,3,3-hexafluoropropane (431-63-0) + 1,1,1,3,3,3-hexafluoropropane (690-39-1) + 2-chloro-1,1,1,3,3,3-hexafluoropropane (431-87-8,134308-72-8) + 1,1,1,2-tetrafluoropropane (421-48-7) + 1-chloro-1,1,2,3,3,3-hexafluoro-propane (359-58-0) + 1,1,1,2,2-pentafluoropropane (1814-88-6) + CF3CClFCHF2 (51346-64-6)

Guidance literature:

With hydrogen fluoride; 1percent Pd supported on fluorided alumina catalyst; at 125 - 300 ℃; for 0.00833333h; under 760.051 Torr; Product distribution / selectivity; Gas phase;

Reference yield:

1,1,1,2,3-pentafluoropropane (431-31-2) → 1,1,1-trifluoropropane (421-07-8) + 1,1-difluoropropene (430-63-7) + 2,3,3,3-tetrafluoro-propene (754-12-1) + 1,1,1,2-tetrafluoropropane (421-48-7)

Guidance literature:

With triethylsilane; In neat (no solvent); at 70 ℃; for 168h; Overall yield = ~ 99 percentSpectr.; Schlenk technique;

DOI:10.3762/BJOC.16.213

upstream raw materials:

Methyl fluoride

1,1,2-trifluoroethylene

1,1,2-trichloro-1,2,3,3,3-pentafluoropropane

3,3-dichloro-1,1,1,2,2-pentafluoropropane

Downstream raw materials:

1,1,1-trifluoropropylene

1,1,1-trifluoropropane

1,1-difluoropropene

Refernces

• 1、 -. "METHOD FOR PRODUCING HYDROFLUOROOLEFIN". Paragraph 0156-0163. . Retrieved 2017/09/30.
• 2、 -. "HYDROGEN FLUORIDE-HFC-254EB AZEOTROPE AND ITS USES". Page/Page column 15. . Retrieved 2011/05/11.