D,L-SULFORAPHANE GLUTATHIONE

Base Information

• Chemical Name: D,L-SULFORAPHANE GLUTATHIONE
• CAS No.: 289711-21-3
• Molecular Formula: C₁₆H₂₈N₄O₇S₃
• Molecular Weight: 484.619
• Mol file: 289711-21-3.mol

Synonyms:D,L-SULFORAPHANE GLUTATHIONE;L-Glutamyl-S-[[[4-(methylsulfinyl)butyl]amino]thioxomethyl]-L-cysteinyl-glycine;SFN-GSH

Chemical Property of D,L-SULFORAPHANE GLUTATHIONE

Chemical Property:

• Melting Point: 157-160°C
• Refractive Index: 1.619
• PSA: 264.52000
• Density: 1.445g/cm³
• LogP: 1.36920
• Storage Temp.: -20°C Freezer
• Solubility.: Water (Slightly), Methanol (Slightly, Heated, Sonicated)

Purity/Quality:

98%Min ^*data from raw suppliers

D,L-Sulforaphane Glutathione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: The major metabolite of Sulforaphane. The Glutathione adduct of Sulforaphane. The major metabolite of Sulforaphane. The Glutathione adduct of Sulforaphane

Technology Process of D,L-SULFORAPHANE GLUTATHIONE

There total 1 articles about D,L-SULFORAPHANE GLUTATHIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

D,L-sulforaphane (4478-93-7) + GLUTATHIONE (70-18-8) → (11R,16S)-16-amino-11-((carboxymethyl)carbamoyl)-13-oxo-8-methylsulfinyl-2,9-dithia-7,12-diazaheptadecan-17-oic acid (289711-21-3)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 23 ℃; for 1h; pH=7 - 8;

DOI:10.1016/j.bmc.2018.12.026

upstream raw materials:

D,L-sulforaphane

GLUTATHIONE

Refernces

• 1、 Boehm, Jeffrey,Davis, Roderick,Murar, Claudia E.,Li, Tindy,McCleland, Brent,Dong, Shuping,Yan, Hongxing,Kerns, Jeffrey,Moody, Christopher J.,Wilson, Anthony J.,Graves, Alan P.,Mentzer, Mary,Qi, Hongwei,Yonchuk, John,Kou, Jen-Pyng,Foley, Joseph,Sanchez, Yolanda,Podolin, Patricia L.,Bolognese, Brian,Booth-Genthe, Catherine,Galop, Marc,Wolfe, Lawrence,Carr, Robin,Callahan, James F.. "Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo". supporting information. p. 579 - 588. Retrieved 2019/01/08.