Technology Process of (2E,2'E)-ethane-1,2-diyl bis(3-(1-benzoyl-1H-indol-2-yl)acrylate)
There total 3 articles about (2E,2'E)-ethane-1,2-diyl bis(3-(1-benzoyl-1H-indol-2-yl)acrylate) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
N-benzoylindole;
With
silver hexafluoroantimonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; copper(II) acetate monohydrate;
In
1,2-dichloro-ethane;
for 0.0166667h;
ethylene glycol diacrylate;
In
1,2-dichloro-ethane;
at 100 ℃;
for 6h;
regioselective reaction;
DOI:10.1021/ol4011486
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide; tetrabutylammomium bromide / dichloromethane / 1.5 h
2.1: [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; silver hexafluoroantimonate; copper(II) acetate monohydrate / 1,2-dichloro-ethane / 0.02 h
2.2: 6 h / 100 °C
With
silver hexafluoroantimonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; tetrabutylammomium bromide; copper(II) acetate monohydrate; sodium hydroxide;
In
dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/ol4011486
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide; tetrabutylammomium bromide / dichloromethane / 1.5 h
2.1: [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; silver hexafluoroantimonate; copper(II) acetate monohydrate / 1,2-dichloro-ethane / 0.02 h
2.2: 6 h / 100 °C
With
silver hexafluoroantimonate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; tetrabutylammomium bromide; copper(II) acetate monohydrate; sodium hydroxide;
In
dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/ol4011486