ETHYL 6-AMINOHEXANOATE

Base Information

• Chemical Name: ETHYL 6-AMINOHEXANOATE
• CAS No.: 371-34-6
• Molecular Formula: C8H17 N O2
• Molecular Weight: 159.228
• Hs Code.: 2922499990
• Mol file: 371-34-6.mol

Synonyms:6-Aminocaproicacid ethyl ester; 6-Aminohexanoic acid ethyl ester; Ethyl 6-aminocaproate;Ethyl 6-aminohexanoate; Ethyl e-aminocaproate

Chemical Property of ETHYL 6-AMINOHEXANOATE

Chemical Property:

• Vapor Pressure: 0.183mmHg at 25°C
• Refractive Index: 1.442
• Boiling Point: 211.4°Cat760mmHg
• PKA: 10.52±0.10(Predicted)
• Flash Point: 80.7°C
• PSA: 52.32000
• Density: 0.949g/cm³
• LogP: 1.76890
• Sensitive.: Air Sensitive

Purity/Quality:

98%Min ^*data from raw suppliers

Ethyl6-Aminohexanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ethyl 6-aminohexanoate is used as pharmaceutical intermediate.

Technology Process of ETHYL 6-AMINOHEXANOATE

There total 3 articles about ETHYL 6-AMINOHEXANOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C12H21N3 (185350-62-3) + 1-amino-5-cyanopentane (2432-74-8) → caprolactam (105-60-2,9012-16-2) + ethyl 6-aminohexanoate (371-34-6)

Guidance literature:

With water; titanium(IV) oxide; In ethanol; at 230 ℃; under 60006 Torr;

Reference yield: 80.0%

C12H21N3 (185350-62-3) → caprolactam (105-60-2,9012-16-2) + 1-amino-5-cyanopentane (2432-74-8) + ethyl 6-aminohexanoate (371-34-6)

Guidance literature:

With water; titanium(IV) oxide; In ethanol; at 230 ℃; under 60006 Torr;

Reference yield:

caprolactam (105-60-2,9012-16-2) + ethanol (64-17-5) → ethyl 6-aminohexanoate (371-34-6) + 6-aminohexanoic acid (60-32-2,93208-38-9)

Guidance literature:

hydrogenchloride; at 350 ℃; for 0.0416667h; under 54005.4 Torr;

upstream raw materials:

C₁₂H₂₁N₃

1-amino-5-cyanopentane

caprolactam

ethanol

Downstream raw materials:

2,4-Dichlor-6-(5-aethoxycarbonylpentylamino)-s-triazin

6-(2-Amino-4-chloro-3-hydroxy-benzoylamino)-hexanoic acid

N-(5-carboxypentyl)-2-nitro-3-hydroxy-4-chlorobenzamide

N-(6-phenylsulfanylcarbonylamino-hexanoyl)-DL-alanine methyl ester

Refernces

• 1、 -. "Process for preparing amino acid esters and their acid addition salts". Page/Page column 3-4. . Retrieved 2008/06/13.