Acetonitrile, (2-amino-m-tolyl)- (7CI)

Base Information

• Chemical Name: Acetonitrile, (2-amino-m-tolyl)- (7CI)
• CAS No.: 90765-18-7
• Molecular Formula: C9H10 N2
• Molecular Weight: 146.1891
• Mol file: 90765-18-7.mol

Synonyms:Acetonitrile,(2-amino-m-tolyl)- (7CI)

Chemical Property of Acetonitrile, (2-amino-m-tolyl)- (7CI)

Chemical Property:

• PSA: 49.81000
• LogP: 2.22448

Purity/Quality:

(2-Amino-3-methyl-phenyl)-acetonitrile ＞97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetonitrile, (2-amino-m-tolyl)- (7CI)

There total 4 articles about Acetonitrile, (2-amino-m-tolyl)- (7CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Methyl-2-nitrobenzyl cyanide (91192-25-5) → <2-Amino-3-methyl-phenyl>-acetonitril (90765-18-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 24h; under 2280 Torr;

Reference yield:

2,6-dimethylnitrobenzene (81-20-9) → <2-Amino-3-methyl-phenyl>-acetonitril (90765-18-7)

Guidance literature:

Multi-step reaction with 4 steps

1: KOEt / diethyl ether / 26 h / Heating

2: (i) aq. KOH, (ii) NH₂OH*HCl, aq. NaOH

3: Ac₂O / acetic acid / 70 °C

4: H₂ / Pd-C / ethanol / 24 h / 2280 Torr

With potassium ethoxide; hydrogen; acetic anhydride; palladium on activated charcoal; In diethyl ether; ethanol; acetic acid;

Reference yield:

(2-Nitro-3-methyl-phenyl)-brenztraubensaeure-oxim → <2-Amino-3-methyl-phenyl>-acetonitril (90765-18-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Ac₂O / acetic acid / 70 °C

2: H₂ / Pd-C / ethanol / 24 h / 2280 Torr

With hydrogen; acetic anhydride; palladium on activated charcoal; In ethanol; acetic acid;

upstream raw materials:

3-Methyl-2-nitrobenzyl cyanide

2,6-dimethylnitrobenzene

ethyl 3-(3-methyl-2-nitrophenyl)-2-oxopropanoate