(2-Chloro-4-(trifluoromethyl)phenyl)hydrazine

Base Information

• Chemical Name: (2-Chloro-4-(trifluoromethyl)phenyl)hydrazine
• CAS No.: 86398-98-3
• Molecular Formula: C7H6 Cl F3 N2
• Molecular Weight: 210.586
• Hs Code.: 2928000090
• European Community (EC) Number: 813-267-0
• DSSTox Substance ID: DTXSID40371529
• Nikkaji Number: J308.002A
• Wikidata: Q82158882
• Mol file: 86398-98-3.mol

Synonyms:86398-98-3;(2-Chloro-4-(trifluoromethyl)phenyl)hydrazine;1-[2-chloro-4-(trifluoromethyl)phenyl]hydrazine;2-Chloro-4-(trifluoromethyl)phenyl hydrazine;[2-chloro-4-(trifluoromethyl)phenyl]hydrazine;2-Chloro-4-(trifluoromethyl)phenylhydrazine;Hydrazine, [2-chloro-4-(trifluoromethyl)phenyl]-;1-(2-chloro-4-(trifluoromethyl)phenyl)hydrazine;SCHEMBL1132575;DTXSID40371529;MFCD00052916;AKOS012978537;SB76804;2-chloro-4-trifluoromethylphenylhydrazine;2-chloro-4-trifluoromethyl-phenylhydrazine;CS-0317062;FT-0611742;EN300-275464

Chemical Property of (2-Chloro-4-(trifluoromethyl)phenyl)hydrazine

Chemical Property:

• Melting Point: 39oC
• Boiling Point: 80-85oC 0,25mm
• PKA: 3.89±0.27(Predicted)
• PSA: 38.05000
• Density: 1.487±0.06 g/cm3(Predicted)
• LogP: 3.41770
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 210.0171604
• Heavy Atom Count: 13
• Complexity: 174

Purity/Quality:

98%min ^*data from raw suppliers

1-[2-Chloro-4-(trifluoromethyl)phenyl]hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 23-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C(F)(F)F)Cl)NN

Technology Process of (2-Chloro-4-(trifluoromethyl)phenyl)hydrazine

There total 5 articles about (2-Chloro-4-(trifluoromethyl)phenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,2-dichloro-4-(trifluoromethyl)benzene (328-84-7) → 2-chloro-4-trifluoromethylphenyl hydrazine (86398-98-3)

Guidance literature:

Reference yield:

2,6-Dichloro-4-trifluoromethylphenylaniline → 2,6-dichloro-4-(trifluoromethyl)phenyl hydrazine (86398-94-9) + 2-chloro-4-trifluoromethylphenyl hydrazine (86398-98-3)

Guidance literature:

With ammonium hydroxide; stannous chloride; sodium nitrite; In hydrogenchloride; sulfuric acid; acetic acid;

Reference yield:

ammonium hydroxide (1336-21-6) + 2,6-Dichloro-4-trifluoromethylphenylaniline → 2,6-dichloro-4-(trifluoromethyl)phenyl hydrazine (86398-94-9) + 2-chloro-4-trifluoromethylphenyl hydrazine (86398-98-3)

Guidance literature:

With stannous chloride; sodium nitrite; In hydrogenchloride; sulfuric acid; acetic acid;

upstream raw materials:

1,2-dichloro-4-(trifluoromethyl)benzene

2-chloro-4-(trifluoromethyl)aniline

ammonium hydroxide

Downstream raw materials:

5-chloro-2-[2-chloro-4-(trifluoromethyl)phenyl]-4-hydroxy-pyridazin-3-one

4-chloro-2-[2-chloro-4-(trifluoromethyl)phenyl]-5-methoxy-pyridazin-3-one

5-chloro-2-[2-chloro-4-(trifluoromethyl)phenyl]-4-methoxy-pyridazin-3-one

4,5-dichloro-2-[2-chloro-4-(trifluoromethyl)phenyl]pyridazin-3-one

Refernces

• 1、 -. "Derivatives of N-phenylpyrazoles". . . Retrieved 2008/06/13.
• 2、 -. "5-Acylamino-4-cyano-1-phenylpyrazole derivatives and use as herbicides". . . Retrieved 2008/06/13.