diphenylacetic acid 4-(2-acetoxy-1-methyl-vinyl)-2-phenyl-thiazol-5-yl ester

Base Information

• Chemical Name: diphenylacetic acid 4-(2-acetoxy-1-methyl-vinyl)-2-phenyl-thiazol-5-yl ester
• CAS No.: 35317-71-6
• Molecular Formula: C₂₈H₂₃NO₄S
• Molecular Weight: 469.561
• Mol file: 35317-71-6.mol

Synonyms:

Chemical Property of diphenylacetic acid 4-(2-acetoxy-1-methyl-vinyl)-2-phenyl-thiazol-5-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of diphenylacetic acid 4-(2-acetoxy-1-methyl-vinyl)-2-phenyl-thiazol-5-yl ester

There total 2 articles about diphenylacetic acid 4-(2-acetoxy-1-methyl-vinyl)-2-phenyl-thiazol-5-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(thiobenzoyl)glycine (2584-64-7) → diphenylacetic acid 4-(2-acetoxy-1-methyl-vinyl)-2-phenyl-thiazol-5-yl ester (35317-71-6)

Guidance literature:

Multi-step reaction with 2 steps

1: PBr₃ / diethyl ether

2: (i) Pb(OAc)2, THF, (ii) /BRN= 1211588/, Et₃N, toluene

With phosphorus tribromide; In diethyl ether;

DOI:10.1039/P19720000310

Reference yield:

diphenylacetic acid chloride (1871-76-7) + 2-phenyl-3-thiazolin-5-one (16446-29-0) + Acetol acetate (592-20-1) → diphenylacetic acid 4-(2-acetoxy-1-methyl-vinyl)-2-phenyl-thiazol-5-yl ester (35317-71-6)

Guidance literature:

Multistep reaction; (i) Pb(OAc)2, THF, (ii) /BRN= 1211588/, Et₃N, toluene;

DOI:10.1039/P19720000310

upstream raw materials:

diphenylacetic acid chloride

2-phenyl-3-thiazolin-5-one

Acetol acetate

N-(thiobenzoyl)glycine