Phenylalanine betaine

Base Information

• Chemical Name: Phenylalanine betaine
• CAS No.: 56755-22-7
• Molecular Formula: C12H17NO2
• Molecular Weight: 207.26900
• Mol file: 56755-22-7.mol

Synonyms:N,N,N-trimethylphenylalanine;L-N,N,N-trimethylphenylalanine;phenylalanine betaine;2-phenylalanine betaine;

Chemical Property of Phenylalanine betaine

Chemical Property:

• PSA: 40.13000
• LogP: 0.05380

Purity/Quality:

98%Min ^*data from raw suppliers

Phenylalaninebetaine ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenylalanine betaine

There total 9 articles about Phenylalanine betaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

L-phenylalanine (63-91-2,25191-15-5,658-69-5,67675-33-6) + O-Methyl-N,N'-diisopropylisourea (54648-79-2) → L-N,N,N-trimethylphenylalanine (56755-22-7,129519-80-8)

Guidance literature:

In methanol; for 312h; Ambient temperature;

DOI:10.1016/S0040-4020(01)89759-3

Reference yield: 37.0%

O-Methyl-N,N'-diisopropylisourea (54648-79-2) + D-β-Phenyl-α-alanine (673-06-3,25191-15-5,658-69-5,67675-33-6) → C12H17NO2 (56755-22-7,129519-80-8)

Guidance literature:

In methanol; for 312h; Ambient temperature;

DOI:10.1016/S0040-4020(01)89759-3

Reference yield:

L-phenylalanine (63-91-2,25191-15-5,658-69-5,67675-33-6) + methyl iodide (74-88-4) → L-N,N,N-trimethylphenylalanine (56755-22-7,129519-80-8)

Guidance literature:

With potassium carbonate; In methanol; for 6h; Heating;

upstream raw materials:

O-Methyl-N,N'-diisopropylisourea

D-β-Phenyl-α-alanine

(1-benzyl-2-hydroxy-ethyl)-trimethyl-ammonium; iodide

L-phenylalanine

Refernces

• 1、 Naresh Chary,Dinesh Kumar, Ch.,Vairamani,Prabhakar. "Characterization of amino acid-derived betaines by electrospray ionization tandem mass spectrometry". experimental part. p. 79 - 88. Retrieved 2012/05/04.
• 2、 Iyengar, R. R.,Bhattacharya, P. K.. "Thermodynamic view of hydrophobic association of side chains of aromatic amino acids". . p. 445 - 451. Retrieved 2007/10/02.