1α,1β,17α-Trihydroxy-21-acetoxy-A-nor-Δ³⁽⁵⁾-pregnentrion-(2,11,20)

Base Information

• Chemical Name: 1α,1β,17α-Trihydroxy-21-acetoxy-A-nor-Δ³⁽⁵⁾-pregnentrion-(2,11,20)
• CAS No.: 14411-14-4
• Molecular Formula: C₂₂H₂₈O₈
• Molecular Weight: 420.46
• Mol file: 14411-14-4.mol

Synonyms:

Chemical Property of 1α,1β,17α-Trihydroxy-21-acetoxy-A-nor-Δ³⁽⁵⁾-pregnentrion-(2,11,20)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1α,1β,17α-Trihydroxy-21-acetoxy-A-nor-Δ³⁽⁵⁾-pregnentrion-(2,11,20)

There total 2 articles about 1α,1β,17α-Trihydroxy-21-acetoxy-A-nor-Δ³⁽⁵⁾-pregnentrion-(2,11,20) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1α,2α,17α-Trihydroxy-21-acetoxy-Δ4-pregnantrion-(3,11,20) (14945-34-7) → 1α,1β,17α-Trihydroxy-21-acetoxy-A-nor-Δ3(5)-pregnentrion-(2,11,20) (14411-14-4)

Guidance literature:

With manganese(IV) oxide; In acetone;

DOI:10.1016/0040-4020(67)85047-6

Reference yield:

prednisone acetate (125-10-0) → 1α,1β,17α-Trihydroxy-21-acetoxy-A-nor-Δ3(5)-pregnentrion-(2,11,20) (14411-14-4)

Guidance literature:

Multi-step reaction with 2 steps

1: OsO₄, Py

2: MnO₂ / acetone

With pyridine; manganese(IV) oxide; osmium(VIII) oxide; In acetone;

DOI:10.1016/0040-4020(67)85047-6

upstream raw materials:

1α,2α,17α-Trihydroxy-21-acetoxy-Δ⁴-pregnantrion-(3,11,20)

prednisone acetate