Technology Process of C23H28N4O4
There total 1 articles about C23H28N4O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-aminopyridin-3-carboxylic acid; N-(tert-butoxycarbonyl)-2(S)-aminobutyric acid;
With
4-methyl-morpholine; isobutyl chloroformate;
In
dichloromethane;
at -20 - 20 ℃;
for 20h;
4-Ethoxyaniline;
In
dichloromethane;
at 20 ℃;
for 24h;
With
4-methyl-morpholine; isobutyl chloroformate;
In
dichloromethane;
at 20 ℃;
for 2h;
DOI:10.1002/cmdc.201200184
- Guidance literature:
-
Multi-step reaction with 3 steps
1: trifluoroacetic acid / dichloromethane
2: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 20 h / 20 °C
3: 2-(1H-9-azabenzotriazol-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 h / 45 °C
With
2-(1H-9-azabenzotriazol-1-yl)-1,1,3,3-tetramethyluroniumhexafluorophosphate; sodium tris(acetoxy)borohydride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1002/cmdc.201200184