N-(N-benzyloxycarbonyl-L-γ-glutamyl)-glycine

Base Information

• Chemical Name: N-(N-benzyloxycarbonyl-L-γ-glutamyl)-glycine
• CAS No.: 97261-93-3
• Molecular Formula: C₁₅H₁₈N₂O₇
• Molecular Weight: 338.317
• Mol file: 97261-93-3.mol

Synonyms:

Chemical Property of N-(N-benzyloxycarbonyl-L-γ-glutamyl)-glycine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(N-benzyloxycarbonyl-L-γ-glutamyl)-glycine

There total 8 articles about N-(N-benzyloxycarbonyl-L-γ-glutamyl)-glycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzyloxycarbonyl-L-glutamic acid-5-hydrazide (4510-09-2) → N-(N-benzyloxycarbonyl-L-γ-glutamyl)-glycine (97261-93-3)

Guidance literature:

With potassium hydrogencarbonate; ethyl acetate; glycine; Reagens 4: H₂O;

DOI:10.1039/jr9500001954

Reference yield:

N-(N-benzyloxycarbonyl-γ-L-glutamyl)-glycine ethyl ester (25352-68-5) → N-(N-benzyloxycarbonyl-L-γ-glutamyl)-glycine (97261-93-3)

Guidance literature:

With potassium hydroxide;

DOI:10.1038/163604b0

Reference yield:

(S)-2-(benzyloxycarbonylamino)-5-ethoxy-5-oxopentanoic acid (35726-62-6,1029401-62-4) → N-(N-benzyloxycarbonyl-L-γ-glutamyl)-glycine (97261-93-3)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous ethanol; hydrazine hydrate / 20 °C

2: aqueous HCl; chloroform; NaNO₂ / 0 °C / Umsetzung des gebildeten Azids mit Glycin-aethylester in Chloroform

3: aqueous KOH

With hydrogenchloride; potassium hydroxide; ethanol; chloroform; hydrazine hydrate; sodium nitrite;

DOI:10.1038/163604b0

upstream raw materials:

N-benzyloxycarbonyl-L-glutamic acid-5-hydrazide

N-(N-benzyloxycarbonyl-γ-L-glutamyl)-glycine ethyl ester

glycine ethyl ester hydrochloride

benzyl (R)-(2,6-dioxotetrahydro-2H-pyran-3-yl)carbamate

Downstream raw materials:

(S)-2-Amino-4-(carboxymethyl-carbamoyl)-butyric acid

Refernces