N-3-(benzoylamino-4-methoxyphenylaminocarbonothioyl)-3,4,5-trimethoxybenzamide

Base Information

• Chemical Name: N-3-(benzoylamino-4-methoxyphenylaminocarbonothioyl)-3,4,5-trimethoxybenzamide
• CAS No.: 1192928-00-9
• Molecular Formula: C₂₅H₂₅N₃O₆S
• Molecular Weight: 495.556
• Mol file: 1192928-00-9.mol

Synonyms:

Chemical Property of N-3-(benzoylamino-4-methoxyphenylaminocarbonothioyl)-3,4,5-trimethoxybenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-3-(benzoylamino-4-methoxyphenylaminocarbonothioyl)-3,4,5-trimethoxybenzamide

There total 3 articles about N-3-(benzoylamino-4-methoxyphenylaminocarbonothioyl)-3,4,5-trimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzoic acid-(2-methoxy-5-nitro-anilide) (34326-53-9) → N-3-(benzoylamino-4-methoxyphenylaminocarbonothioyl)-3,4,5-trimethoxybenzamide (1192928-00-9)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; ammonium formate / isopropyl alcohol / Inert atmosphere; Microwave irradiation

2: acetone / 1 h / Inert atmosphere; Reflux

With palladium 10% on activated carbon; ammonium formate; In isopropyl alcohol; acetone;

DOI:10.1021/jm2013369

Reference yield:

(3,4,5-trimethoxy)benzoyl isothiocyanate (6939-63-5) + 5-amino-2-methoxy-N-phenylbenzamide (119-88-0) → N-3-(benzoylamino-4-methoxyphenylaminocarbonothioyl)-3,4,5-trimethoxybenzamide (1192928-00-9)

Guidance literature:

In acetone; for 1h; Inert atmosphere; Reflux;

DOI:10.1021/jm2013369

Reference yield:

3,4,5-Trimethoxybenzoyl chloride (4521-61-3) → N-3-(benzoylamino-4-methoxyphenylaminocarbonothioyl)-3,4,5-trimethoxybenzamide (1192928-00-9)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 0.33 h / Inert atmosphere; Reflux

2: acetone / 1 h / Inert atmosphere; Reflux

In acetone;

DOI:10.1021/jm2013369

upstream raw materials:

benzoic acid-(2-methoxy-5-nitro-anilide)

3,4,5-Trimethoxybenzoyl chloride

(3,4,5-trimethoxy)benzoyl isothiocyanate

5-amino-2-methoxy-N-phenylbenzamide

Refernces