C₆₇H₈₅N₁₅O₉S

Base Information

• Chemical Name: C₆₇H₈₅N₁₅O₉S
• CAS No.: 1435485-71-4
• Molecular Formula: C₆₇H₈₅N₁₅O₉S
• Molecular Weight: 1276.57
• Mol file: 1435485-71-4.mol

Synonyms:

Chemical Property of C₆₇H₈₅N₁₅O₉S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Useful:

Technology Process of C₆₇H₈₅N₁₅O₉S

There total 1 articles about C₆₇H₈₅N₁₅O₉S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C26H28N2O3 (1435485-68-9) + N-α-Fmoc-N-ε-[5-(dimethylamino)naphthalene-1-sulfonyl]-L-lysine (118584-90-0) + 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester (143824-78-6,163619-04-3) + Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine (187618-60-6) → C67H85N15O9S (1435485-71-4)

Guidance literature:

Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 1.5h;

With piperidine; In N,N-dimethyl-formamide; Wang resin

C₂₆H₂₈N₂O₃; N-α-Fmoc-N-ε-[5-(dimethylamino)naphthalene-1-sulfonyl]-L-lysine; 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester; Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine; Further stages;

DOI:10.1021/ml400073g

Reference yield:

C67H85N15O9S (1435485-71-4) + L-tryptophane benzyl ester (4299-69-8,141595-98-4) → C85H101N17O10S (1435485-80-5)

Guidance literature:

With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3h;

DOI:10.1021/ml400073g

upstream raw materials:

C₂₆H₂₈N₂O₃

N-α-Fmoc-N-ε-[5-(dimethylamino)naphthalene-1-sulfonyl]-L-lysine

3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester

Nα-(9-fluorenylmethyloxycarbonyl)-Nγ-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine

Downstream raw materials:

C₈₅H₁₀₁N₁₇O₁₀S

Refernces