4-amino-2,6-dichloro-3,5-dinitropyridine

Base Information

• Chemical Name: 4-amino-2,6-dichloro-3,5-dinitropyridine
• CAS No.: 650140-90-2
• Molecular Formula: C₅H₂Cl₂N₄O₄
• Molecular Weight: 253.001
• Mol file: 650140-90-2.mol

Synonyms:

Chemical Property of 4-amino-2,6-dichloro-3,5-dinitropyridine

Chemical Property:

• Boiling Point: 466.9±40.0 °C(Predicted)
• PKA: -7.85±0.50(Predicted)
• Density: 1.909±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

4-AMINO-2,6-DICHLORO-3,5-DINITROPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-amino-2,6-dichloro-3,5-dinitropyridine

There total 5 articles about 4-amino-2,6-dichloro-3,5-dinitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2,6-dichloro-[4]pyridylamine (2587-02-2) → 4-amino-2,6-dichloro-3,5-dinitropyridine (650140-90-2)

Guidance literature:

With sulfuric acid; nitric acid; at 80 - 85 ℃;

DOI:10.1016/j.mencom.2022.01.037

Reference yield: 43.0%

2,6-dichloro-[4]pyridylamine (2587-02-2) → 4-amino-2,6-dichloro-3,5-dinitropyridine (650140-90-2) + 2,6-dichloro-3-nitropyridin-4-amine (2897-43-0)

Guidance literature:

With sulfuric acid; potassium nitrate; at 20 ℃; for 6h;

DOI:10.1515/hc-2016-0132

Reference yield:

2,6-dichloropyridine (2402-78-0) → 4-amino-2,6-dichloro-3,5-dinitropyridine (650140-90-2)

Guidance literature:

Multi-step reaction with 4 steps

1: urea hydrogen peroxide adduct; trifluoroacetic anhydride / dichloromethane / 6.5 h / 0 - 20 °C

2: sulfuric acid; potassium nitrate / 7 h / 20 - 100 °C

3: acetic acid; iron / 3 h / 45 °C

4: sulfuric acid / 7 h / 20 - 50 °C

With sulfuric acid; urea hydrogen peroxide adduct; iron; acetic acid; potassium nitrate; trifluoroacetic anhydride; In dichloromethane;

DOI:10.1515/hc-2016-0132

upstream raw materials:

2,6-dichloro-[4]pyridylamine

2,6-dichloropyridine

2,6-dichloropyridine N-oxide

4-nitro-2,6-dichloro-pyridine

Downstream raw materials:

2,4,6-triamino-3,5-dinitropyridine

Refernces

• 1、 Gilmanov, Ruslan Z.,Khayrutdinov, Farit G.,Nikitin, Valeriy G.,Sheremetev, Aleksei B.,Strizhenko, Kirill V.,Suponitsky, Kyrill Yu.. "Bis(furazano)pyridinone N,N'-dioxide: a new high-density insensitive explosive". . p. 114 - 116. Retrieved 2022/03/08.