3-aminomethyl-4-<3-(o-chlorobenzoyl)-5-ethylthiophen-2-yl>-5-methyl-4H-1,2,4-triazole hydrochloride

Base Information

• Chemical Name: 3-aminomethyl-4-<3-(o-chlorobenzoyl)-5-ethylthiophen-2-yl>-5-methyl-4H-1,2,4-triazole hydrochloride
• CAS No.: 69298-45-9
• Molecular Formula: C₁₇H₁₇ClN₄OS*ClH
• Molecular Weight: 397.328
• Mol file: 69298-45-9.mol

Synonyms:

Chemical Property of 3-aminomethyl-4-<3-(o-chlorobenzoyl)-5-ethylthiophen-2-yl>-5-methyl-4H-1,2,4-triazole hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-aminomethyl-4-<3-(o-chlorobenzoyl)-5-ethylthiophen-2-yl>-5-methyl-4H-1,2,4-triazole hydrochloride

There total 1 articles about 3-aminomethyl-4-<3-(o-chlorobenzoyl)-5-ethylthiophen-2-yl>-5-methyl-4H-1,2,4-triazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

etizolam (40054-69-1) → 3-aminomethyl-4-<3-(o-chlorobenzoyl)-5-ethylthiophen-2-yl>-5-methyl-4H-1,2,4-triazole hydrochloride (69298-45-9)

Guidance literature:

With hydrogenchloride; for 20h; Ambient temperature;

DOI:10.1248/cpb.40.220

Reference yield:

3-aminomethyl-4-<3-(o-chlorobenzoyl)-5-ethylthiophen-2-yl>-5-methyl-4H-1,2,4-triazole hydrochloride (69298-45-9) → [2-(3-Aminomethyl-5-methyl-[1,2,4]triazol-4-yl)-5-ethyl-thiophen-3-yl]-(2-chloro-phenyl)-methanol (140632-75-3)

Guidance literature:

With sodium tetrahydroborate; for 0.0833333h; Yield given;

DOI:10.1248/cpb.40.220

upstream raw materials:

etizolam

Downstream raw materials:

[2-(3-Aminomethyl-5-methyl-[1,2,4]triazol-4-yl)-5-ethyl-thiophen-3-yl]-(2-chloro-phenyl)-methanol

Refernces