D-Tyrosine, N-acetyl-, ethyl ester

Base Information

• Chemical Name: D-Tyrosine, N-acetyl-, ethyl ester
• CAS No.: 16720-61-9
• Molecular Formula: C13H17NO4
• Molecular Weight: 251.282
• Mol file: 16720-61-9.mol

Synonyms:N-Acetyl-D-tyrosin-aethylester;L-N-acetyltyrosine ethyl ester;N-acetyl-D-tyrosine ethyl ester;

Chemical Property of D-Tyrosine, N-acetyl-, ethyl ester

Chemical Property:

• PSA: 75.63000
• LogP: 1.39340

Purity/Quality:

N-ACETYL-D-TYROSINE ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D-Tyrosine, N-acetyl-, ethyl ester

There total 4 articles about D-Tyrosine, N-acetyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

ethanol (64-17-5) + N-acetyl-L-tyrosine (537-55-3) → N-acetyl-L-tyrosine ethyl ester (840-97-1,16720-61-9,30697-69-9)

Guidance literature:

With citrate-phosphate buffer at pH 4.2; α-chymotripsin; In chloroform;

DOI:10.1016/S0040-4020(01)91818-6

Reference yield: 43.0%

ethyl N-acetyl-tyrosinate (30697-69-9) → N-acetyl-L-tyrosine (537-55-3) + N-acetyl-D-tyrosine ethyl ester (16720-61-9)

Guidance literature:

With water; In ethanol; at 25 ℃; for 48h; optical yield given as %ee; enantioselective reaction; Microbiological reaction;

DOI:10.1016/j.tetasy.2010.02.011

Reference yield:

ethyl N-acetyl-tyrosinate (30697-69-9) → N-acetyl-D-tyrosine ethyl ester (16720-61-9)

Guidance literature:

With methanol; chymotrypsin; pH 8;

DOI:10.1021/ja01148a041

upstream raw materials:

ethyl N-acetyl-tyrosinate

ethanol

Ac-D-Tyrosine

N-acetyl-L-tyrosine

Downstream raw materials:

N-acetyl-D-tyrosine amide

N-acetyl-D-tyrosine hydrazide

N-acetyl-D-tyrosine hydroxyamide

N-acetyl-O'-(2,3-epoxypropyl)-D-tyrosine ethyl ester

Refernces

• 1、 St?hl, Marianne,Jeppsson-Wistrand, Ulla,M?nsson, Mats-Olle,Mosbach, Klaus. "Induced stereoselectivity and substrate selectivity of bio-imprinted α-chymotrypsin in anhydrous organic media". . p. 9366 - 9368. Retrieved 2007/10/02.