Benzenesulfonic acid, 2-(2-amino-4-chlorophenoxy)-5-chloro-

Base Information

• Chemical Name: Benzenesulfonic acid, 2-(2-amino-4-chlorophenoxy)-5-chloro-
• CAS No.: 42293-27-6
• Molecular Formula: C12H9 Cl2 N O4 S
• Molecular Weight: 334.18
• European Community (EC) Number: 255-752-4
• DSSTox Substance ID: DTXSID3068380
• Nikkaji Number: J278.380K
• Wikidata: Q72434632
• Mol file: 42293-27-6.mol

Synonyms:42293-27-6;2-(2-amino-4-chlorophenoxy)-5-chlorobenzenesulfonic acid;Benzenesulfonic acid, 2-(2-amino-4-chlorophenoxy)-5-chloro-;EINECS 255-752-4;2-(2-Amino-4-chlorophenoxy)-5-chlorobenzenesulphonic acid;2-(2-Amino-4-chlorophenoxy)-5-chlorobenzenesulfonicacid;2-AMINO-4,4'-DICHLORO DIPHENYL ETHER-2'-SULFONIC ACID;SCHEMBL8355710;DTXSID3068380;C12-H9-Cl2-N-O4-S;2-Amino-4,4`-dichloro diphenyl ether-2`-sulfonic acid

Chemical Property of Benzenesulfonic acid, 2-(2-amino-4-chlorophenoxy)-5-chloro-

Chemical Property:

• Density: 1.599g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 332.9629343
• Heavy Atom Count: 20
• Complexity: 428

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-4,4`-dichlorodiphenylether-2`-sulfonicacid 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)N)OC2=C(C=C(C=C2)Cl)S(=O)(=O)O

Technology Process of Benzenesulfonic acid, 2-(2-amino-4-chlorophenoxy)-5-chloro-

There total 4 articles about Benzenesulfonic acid, 2-(2-amino-4-chlorophenoxy)-5-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-2-(4-chloro-2-nitro-phenoxy)-benzenesulfonic acid (68892-04-6) → 2-(2-amino-4-chloro-phenoxy)-5-chloro-benzenesulfonic acid (42293-27-6)

Guidance literature:

With iron; acetic acid;

Reference yield:

4-chloro-1-(4-chlorophenoxy)-2-nitrobenzene (135-12-6) → 2-(2-amino-4-chloro-phenoxy)-5-chloro-benzenesulfonic acid (42293-27-6)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄

2: iron; aqueous acetic acid

With sulfuric acid; iron; acetic acid;

Reference yield:

potassium 4-chlorophenoxide (1121-74-0) → 2-(2-amino-4-chloro-phenoxy)-5-chloro-benzenesulfonic acid (42293-27-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 170 °C

2: H₂SO₄

3: iron; aqueous acetic acid

With sulfuric acid; iron; acetic acid;

upstream raw materials:

5-chloro-2-(4-chloro-2-nitro-phenoxy)-benzenesulfonic acid

4-chloro-1-(4-chlorophenoxy)-2-nitrobenzene

potassium 4-chlorophenoxide

2,5-dichloronitrobenzene