1005759-28-3

Basic information

• Product Name: 5-(3,5-dimethoxyphenyl)-2-n-propylthiazole
• Synonyms: 5-(3,5-dimethoxyphenyl)-2-n-propylthiazole
• CAS NO: 1005759-28-3
• Molecular Weight: 263.36
• Mol File: 1005759-28-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(3,5-dimethoxyphenyl)-2-n-propylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3,5-dimethoxyphenyl)-2-n-propylthiazole(1005759-28-3)
• EPA Substance Registry System: 5-(3,5-dimethoxyphenyl)-2-n-propylthiazole(1005759-28-3)

Safety Data

• Hazardous Substances Data: 1005759-28-3(Hazardous Substances Data)

Upstream product

• 17626-75-4 2-(n-propyl)-thiazole 
• 60319-09-7 3,5-dimethoxyphenyl trifluoromethanesulfonate 

Relevant articles and documents

Aryl triflates: Useful coupling partners for the direct arylation of heteroaryl derivatives via Pd-catalyzed C-H activation-functionalization

Aryl triflates were found to be suitable partners for the palladium catalyzed direct arylation of heteroaromatics via C-H activation- functionalization. The reaction conditions and the catalyst have a determining influence on the yields. The system combining PPh3 and Pd(OAc) 2 using KOAc as base and DMF as solvent promotes the selective 2- or 5-arylations in moderate to high yields. Several heteroaromatics such as furan, thiophene, thiazole or oxazole derivatives have been employed successfully. The electronic properties of the aryl triflates also have a decisive influence on the yields of the coupling products. Electron-rich aryl triflates gave satisfactory results, whereas the electron-poor ones led to the formation of phenols. The Royal Society of Chemistry 2008.