1015255-46-5 Usage
Description
(S)-2-[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylaminopropionic acid methyl ester is a complex organic compound with a unique molecular structure. It is characterized by its chiral centers and various functional groups, which contribute to its potential applications in different fields.
Uses
Used in Pharmaceutical Industry:
(S)-2-[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylaminopropionic acid methyl ester is used as a potential therapeutic agent for the treatment of Hepatitis C Virus. Its unique structure allows it to target specific viral enzymes, inhibiting their activity and thus helping to combat the virus.
Used in Chemical Synthesis:
In the field of chemical synthesis, (S)-2-[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylaminopropionic acid methyl ester can be used as a key intermediate or building block in the synthesis of other complex molecules, such as pharmaceuticals, agrochemicals, or advanced materials.
Used in Research and Development:
Due to its unique structure and potential applications, (S)-2-[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylaminopropionic acid methyl ester can be utilized in research and development for the discovery of new drugs, materials, or chemical processes. Its synthesis and properties can provide valuable insights into the design and development of novel compounds with specific applications.
Used in Quality Control and Impurity Analysis:
As an impurity of Sofosbuvir (P839640), (S)-2-[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy](phenoxy)phosphorylaminopropionic acid methyl ester can be used in quality control and impurity analysis of pharmaceutical products. Understanding and controlling the presence of such impurities is crucial for ensuring the safety, efficacy, and quality of the final drug product.
Check Digit Verification of cas no
The CAS Registry Mumber 1015255-46-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,5,2,5 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1015255-46:
(9*1)+(8*0)+(7*1)+(6*5)+(5*2)+(4*5)+(3*5)+(2*4)+(1*6)=105
105 % 10 = 5
So 1015255-46-5 is a valid CAS Registry Number.
1015255-46-5Relevant articles and documents
The mechanism of action of β-D-2′-deoxy-2′-fluoro- 2′-C-methylcytidine involves a second metabolic pathway leading to β-D-2′-deoxy-2′-fluoro-2′-C-methyluridine 5′-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase
Murakami, Eisuke,Niu, Congrong,Bao, Haiying,Micolochick Steuer, Holly M.,Whitaker, Tony,Nachman, Tammy,Sofia, Michael A.,Wang, Peiyuan,Otto, Michael J.,Furman, Phillip A.
, p. 458 - 464 (2008)
β-D-2′-Deoxy-2′-fluoro-2′-C-methylcytidine (PSI-6130) is a potent inhibitor of hepatitis C virus (HCV) RNA replication in an HCV replicon assay. The 5′-triphosphate of PSI-6130 is a competitive inhibitor of the HCV RNA-dependent RNA polymerase (RdRp) and
NUCLEOSIDE PHOSPHORAMIDATE PRODRUGS
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Page/Page column 36, (2010/02/17)
Disclosed herein are phosphoramidate prodrugs of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomer, salt (acid or basic addition salt), hydrate, solvate, or crystalline form thereof, represented by the following structure: Also disclosed are methods of treatment, uses, and processes for preparing each of which utilize the compound represented by formula I.
