101711-79-9

Basic information

• Product Name: (4S,2'S,3'R)-3-(3'-hydroxy-2'-methylbutanoyl)-4-benzyl-2-oxazolidinone
• Synonyms: (4S,2'S,3'R)-3-(3'-hydroxy-2'-methylbutanoyl)-4-benzyl-2-oxazolidinone
• CAS NO: 101711-79-9
• Molecular Weight: 277.32
• Mol File: 101711-79-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (4S,2'S,3'R)-3-(3'-hydroxy-2'-methylbutanoyl)-4-benzyl-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,2'S,3'R)-3-(3'-hydroxy-2'-methylbutanoyl)-4-benzyl-2-oxazolidinone(101711-79-9)
• EPA Substance Registry System: (4S,2'S,3'R)-3-(3'-hydroxy-2'-methylbutanoyl)-4-benzyl-2-oxazolidinone(101711-79-9)

Safety Data

• Hazardous Substances Data: 101711-79-9(Hazardous Substances Data)

Upstream product

• 90719-27-0 (S)-3-acryloyl-4-benzyloxazolidin-2-one 
• 75-07-0 acetaldehyde 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 131685-53-5 (S)-4-benzyl-3-propionyl-2-oxazolidinone 

Downstream Products

• 101711-80-2 (S)-8-benzyl-3-[(2S,3R)-3-(tert-butyldimethylsilyloxy)-2-methylbutanoyl]oxazolidin-2-one 
• 1401338-12-2 (S)-8-benzyl-3-[(2S,3R)-3-(methoxymethoxy)-2-methylbutanoyl]oxazolidin-2-one 

Relevant articles and documents

Polyoxygenated Tertiary Alcohols: A Kiyooka Approach

A Kiyooka aldol approach for the stereoselective synthesis of tertiary alcohols is presented. This approach allows for the incorporation of different substituents at all three remaining positions at the chiral center bearing the tertiary alcohol. To demon

Substrate-controlled stereoselectivity in the Yamamoto aldol reaction

The Yamamoto aldol reaction is a vinylogous aldol reaction that relies on bulky aluminium-based Lewis acids. These activate both the aldehyde as well as become part of the enolate moiety. The report discloses the first detailed study on the substrate-controlled Yamamoto aldol reaction in which 2,3-syn and 2,3-anti disubstituted aldehydes serve as the stereodirecting elements. The "size" of the substituent in the β-position strongly determines the facial selectivity of enolate addition to the aldehyde. Large substituents favour formation of 1,3-syn diols while slim alkynyl groups preferentially lead to 1,3-anti products. The Royal Society of Chemistry 2012.

Enantiospecific Synthesis of Analogues of the Diketide Intermediate of the Erythromycin Polyketide Synthase (PKS)

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