1017575-24-4

Basic information

• Product Name: benzyl (4S)-4-(2,5-dioxopyrrolidin-1-yloxycarbonylamino)azepane-1-carboxylate
• Synonyms: benzyl (4S)-4-(2,5-dioxopyrrolidin-1-yloxycarbonylamino)azepane-1-carboxylate
• CAS NO: 1017575-24-4
• Molecular Weight: 389.408
• Mol File: 1017575-24-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (4S)-4-(2,5-dioxopyrrolidin-1-yloxycarbonylamino)azepane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (4S)-4-(2,5-dioxopyrrolidin-1-yloxycarbonylamino)azepane-1-carboxylate(1017575-24-4)
• EPA Substance Registry System: benzyl (4S)-4-(2,5-dioxopyrrolidin-1-yloxycarbonylamino)azepane-1-carboxylate(1017575-24-4)

Safety Data

• Hazardous Substances Data: 1017575-24-4(Hazardous Substances Data)

Upstream product

• 74124-79-1 di(succinimido) carbonate 

Downstream Products

• 1017575-57-3 (1S,5R)-2-((4S)-1-benzyloxycarbonylazepan-4-ylaminocarbonyl)-7-oxo-2,6-diazabicyclo[3.2.0]heptane-6-sulfonic acid 
• 1017576-20-3 (1S,5R)-2-((4S)-1-benzyloxycarbonylazepan-4-ylaminocarbonyl)-7-oxo-2,6-diazabicyclo[3.2.0]heptane-6-sulfonic acid, terbutylammonium salt 

Relevant articles and documents

NOVEL INHIBITORS OF BETA-LACTAMASE

A class of 7-oxo-2,6-diazabicyclo-[3.2.0]-heptane-6-sulfonic acid compounds substituted at the two position of the bicyclic ring with a heterocyclylaminocarbonyl group or a carbocyclylaminocarbonyl group are β-lactamase inhibitors. The compounds and their prodrugs and pharmaceutically acceptable salts are useful in the treatment of bacterial infections in combination with β-lactam antibiotics. In particular, the compounds are suitable for use with β-lactam antibiotics (e.g., imipenem and ceftazidime) against micro-organisms resistant to β-lactam antibiotics due to the presence of the β-lactamases.