102274-42-0

Basic information

• Product Name: C₁₃H₁₂BrN₃O₄
• Synonyms: C₁₃H₁₂BrN₃O₄
• CAS NO: 102274-42-0
• Molecular Weight: 354.16
• Mol File: 102274-42-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₂BrN₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₂BrN₃O₄(102274-42-0)
• EPA Substance Registry System: C₁₃H₁₂BrN₃O₄(102274-42-0)

Safety Data

• Hazardous Substances Data: 102274-42-0(Hazardous Substances Data)

Upstream product

• 585-76-2 m-bromobenzoic acid 
• 443-48-1 metronidazole 
• 13182-89-3 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate 

Relevant articles and documents

Metronidazole esters: A new class of antiglycation agents

A series of metronidazole ester derivatives 1-34 has been synthesized with the aim of developing new leads with antiglycation activity. The in vitro evaluation of antiglycation potential of 1-34 showed that the ester derivatives 28, 16, and 3 have IC50 values 218.97 ± 2.5, 245.3 ± 5.1, and 278.6 ± 0.8 μM, respectively, comparable to the standard agent, rutin (IC50 = 294.5 ± 1.50 μM). The study identifies a new class of potent antiglycation agents. A structure-activity relationship has also been evaluated. All the compounds were characterized by using spectroscopic techniques, including 1H NMR, IR, and EI-MS.