102389-96-8

Basic information

• Product Name: (2R,3R)-3-hydroxy-1,2-O-isopropylidene-3-p-methoxyphenyl-1,2-propanediol
• Synonyms: (2R,3R)-3-hydroxy-1,2-O-isopropylidene-3-p-methoxyphenyl-1,2-propanediol
• CAS NO: 102389-96-8
• Molecular Weight: 238.284
• Mol File: 102389-96-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2R,3R)-3-hydroxy-1,2-O-isopropylidene-3-p-methoxyphenyl-1,2-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-3-hydroxy-1,2-O-isopropylidene-3-p-methoxyphenyl-1,2-propanediol(102389-96-8)
• EPA Substance Registry System: (2R,3R)-3-hydroxy-1,2-O-isopropylidene-3-p-methoxyphenyl-1,2-propanediol(102389-96-8)

Safety Data

• Hazardous Substances Data: 102389-96-8(Hazardous Substances Data)

Upstream product

• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 

Downstream Products

• 1022915-05-4 (R)-4-((R)-(4-methoxyphenyl)((2-phenylallyl)oxy)methyl)-2,2-dimethyl-1,3-dioxolane 
• 1632157-51-7 (R)-4-((R)-(4-methoxyphenyl)((2-methylallyl)oxy)methyl)-2,2-dimethyl-1,3-dioxolane 
• 1632157-28-8 C₂₄H₃₂O₅ 
• 1632157-26-6 C₂₄H₃₀O₅ 
• 1632157-22-2 (R)-1-((R)-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)(4-methoxyphenyl)methoxy)-2-phenylpropan-2-ol 
• 1632157-36-8 C₂₂H₂₈O₅ 
• 1632157-54-0 (R)-1-((R)-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)(4-methoxyphenyl)methoxy)-2-methyl-5-(2-methyl-1,3-dioxolan-2-yl)pentan-2-ol 
• 1632157-53-9 (S)-1-((R)-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)(4-methoxyphenyl)methoxy)-2-methyl-5-(2-methyl-1,3-dioxolan-2-yl)pentan-2-ol 
• 1022915-06-5 2-((R)-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)(4-methoxyphenyl)methoxy)-1-phenylethanone 
• 1632157-46-0 C₂₇H₂₉FO₅ 
• 1632157-32-4 C₂₇H₂₉FO₅ 
• 1632157-44-8 C₂₇H₃₆O₅ 
• 1632157-30-2 C₂₇H₃₆O₅ 
• 1632157-38-0 C₂₃H₂₈O₅ 

Relevant articles and documents

A chiral benzyl group as a chiral auxiliary and protecting group for the synthesis of optically active 1,2-Diols and (+)-Frontalin

Chelation-controlled asymmetric nucleophilic addition of a Grignard reagent to chiral α-benzyloxy ketones gives the corresponding alcohols with high diastereoselectivities (up to 96% de) by 1,4-asymmetric induction. A chiral benzyl group is used as a chiral auxiliary as well as a protecting group for the synthesis of optically active 1,2-diols and (+)-frontalin. Georg Thieme Verlag Stuttgart, New York.

Bidentate chelation-controlled asymmetric synthesis of α-hydroxy esters based on the glycolate enolate alkylation

(S)-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl](4-methoxyphenyl)methanol (4b) has been synthesized and evaluated as a chiral auxiliary for the asymmetric synthesis of α-hydroxy esters based on bidentate chelation-controlled alkylation of glycolate enolate. (C) 2000 Elsevier Science Ltd.

Synthesis of the rarely obtained syn-Adducts in the Reaction of Organocopper Compounds with 2,3-O-Isopropylideneglyceraldehyde. Preparation of Optically Active Epoxy Alcohols

Organocopper compounds, prepared from Grignard reagents and copper(I) iodide in tetrahydrofuran-dimethyl sulphide, react with 2,3-O-isopropylideneglyceraldehyde highly stereoselectively (>10:1) affording the rarely obtained syn-addition products which can be readily converted into optically active epoxy alcohols, useful intermediates in organic synthesis.