103-39-9 Usage
Description
2-[(1-methyl-2-phenoxyethyl)amino]ethanol is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its unique molecular structure, which includes a phenoxyethylamine group attached to an ethanol molecule. This structure endows it with specific chemical properties that make it valuable in the development of medications.
Uses
Used in Pharmaceutical Industry:
2-[(1-methyl-2-phenoxyethyl)amino]ethanol is used as a key intermediate in the synthesis of N-α(2-chloroethyl)-1-phenoxy-2-propanamine hydrochloride (C349003), which is identified as Impurity B of the drug Phenoxybenzamine Hydrochloride (P227990). Phenoxybenzamine Hydrochloride is an irreversible α-antagonist that is utilized in the treatment of hypertension. 2-[(1-methyl-2-phenoxyethyl)amino]ethanol exhibits a relatively slow onset and a prolonged effect, distinguishing it from other α-blockers in its class. Its role in the synthesis of this medication highlights the importance of 2-[(1-methyl-2-phenoxyethyl)amino]ethanol in contributing to the development of effective treatments for hypertension.
Check Digit Verification of cas no
The CAS Registry Mumber 103-39-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 103-39:
(5*1)+(4*0)+(3*3)+(2*3)+(1*9)=29
29 % 10 = 9
So 103-39-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO2/c1-10(12-7-8-13)9-14-11-5-3-2-4-6-11/h2-6,10,12-13H,7-9H2,1H3
103-39-9Relevant articles and documents
A PROCESS FOR THE PREPARATION OF PHENOXYBENZAMINE
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, (2018/08/03)
The present invention provides a process for the preparation of N-phenoxyisopropyl ethanolamine of Formula (II) and its conversion to Phenoxybenzamine of Formula (I) or pharmaceutically acceptable salts thereof.