103-94-6 Usage
General Description
2-((4-Nitrophenyl)amino)-2-oxoacetic acid is a chemical compound with the molecular formula C8H6N2O6. It consists of an oxoacetic acid group (-COCH2COOH) with a 4-nitroaniline moiety (4-nitrophenylamino) attached to one of its carbon atoms. It is of interest in organic chemistry and may have applications in various chemical reactions or as an intermediate in the synthesis of other organic compounds.
Description
4-Nitrophenyloxamic Acid, with the chemical formula C6H6N2O4, is an organic compound that belongs to the class of oxamic acids. It is characterized by the presence of a nitro group (-NO2) attached to a phenyl ring and an oxime group (-C(=NOH)OH) attached to the same ring. 4-NITROPHENYLOXAMIC ACID is known for its inhibitory effects on neuraminidase, an enzyme that plays a crucial role in the replication of certain viruses.
Uses
Used in Pharmaceutical Industry:
4-Nitrophenyloxamic Acid is used as an antiviral agent for its inhibitory effects on neuraminidase of Newcastle disease virus Kudu 113 strain. By inhibiting the neuraminidase enzyme, this compound can potentially limit the replication and spread of the virus, making it a valuable tool in the development of antiviral therapies.
Used in Research and Development:
4-Nitrophenyloxamic Acid can be utilized in research settings to study the structure, function, and inhibition of neuraminidase enzymes. This can contribute to a better understanding of the mechanisms underlying viral replication and the development of novel antiviral drugs.
Used in Diagnostic Applications:
Due to its inhibitory effects on neuraminidase, 4-Nitrophenyloxamic Acid can be employed in diagnostic assays to detect the presence of neuraminidase enzymes or the activity of neuraminidase inhibitors. This can be particularly useful in the early detection and monitoring of viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 103-94-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 3 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 103-94:
(5*1)+(4*0)+(3*3)+(2*9)+(1*4)=36
36 % 10 = 6
So 103-94-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H6N2O5/c11-7(8(12)13)9-5-1-3-6(4-2-5)10(14)15/h1-4H,(H,9,11)(H,12,13)
103-94-6Relevant articles and documents
Cerium (IV) mediated oxidative dimerization of 3-oxoacid anilides and their cyclizations
Zaleska,Lis
, p. 189 - 197 (2007/10/03)
Investigation of the behavior of several anilides of 3-oxoacids in oxidation reaction with ceric ammonium nitrate has shown that selective intermolecular C-C bond formation, which led to their dimers, is typical of these compounds. These dimeric species were cyclized in two routes, A and B, leading to 3-[2′-(1′-aniline-3′-oxo)-indene]-quinoline-2-on derivatives with HCl(g) (Route A), and with application of H2SO4 as a cyclization agent, gave furane-3,4-dicarboxylic acid derivatives (Route B).
