103383-72-8

Basic information

• Product Name: Benzene, 2-(difluoromethyl)-1,3,5-trimethyl-
• CAS NO: 103383-72-8
• Molecular Formula: C10H12F2
• Molecular Weight: 170.202
• Mol File: 103383-72-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 2-(difluoromethyl)-1,3,5-trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2-(difluoromethyl)-1,3,5-trimethyl-(103383-72-8)
• EPA Substance Registry System: Benzene, 2-(difluoromethyl)-1,3,5-trimethyl-(103383-72-8)

Safety Data

• Hazardous Substances Data: 103383-72-8(Hazardous Substances Data)

Upstream product

• 108-67-8 1,3,5-trimethyl-benzene 
• 139139-80-3 bis(2,4,6-trimethylphenyl)iodonium triflate 
• 144930-50-7 mesityl(phenyl)iodonium triflouromethanesulfonate 
• 4028-63-1 iodomesitylene 
• 88-05-1 2,4,6-trimethylaniline 
• 41159-04-0 2-mesityl-1,3-dithiolane 
• 487-68-3 mesytaldehyde 

Relevant articles and documents

gem-Difluoro Compounds: A Convenient Preparation from Ketones and Aldehydes by Halogen Fluoride Treatment of 1,3-Dithiolanes

gem-Difluoro compounds can be prepared from ketones and aldehydes by formation of the corresponding 1,3-dithiolanes, followed by reaction with 1,3-dibromo-5,5-dimethylhydantoin and pyridinium poly(hydrogenfluoride) (HF-pyridine) in methylene chloride.The

Well-Defined, Shelf-Stable (NHC)Ag(CF2H) Complexes for Difluoromethylation

The preparation of the thermally stable, well-defined NHC-ligated difluoromethylated silver complexes 1a,b is described. The complexes were fully characterized, and the structural assignments were ambiguously further confirmed by single-crystal X-ray diffraction. Reactions of [(SIPr)Ag(CF2H)] with a variety of activated electrophiles such as diaryliodonium salts, vinyl(aryl)iodonium salts, aryldiazonium salts, and acid chlorides in the presence or absence of CuI occurred smoothly at room temperature to generate difluoromethylated compounds in good to excellent yields. (Chemical Equation Presented).