103490-51-3Relevant articles and documents
Dihydropyridazinone cardiotonics: Synthesis and inotropic activity of 5'-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl) spiro[cycloalkane-1,3'-[3H]indol]-2'(1'H)-ones
Robertson,Krushinski,Pollock,Wilson,Kauffman,Hayes
, p. 824 - 829 (1987)
-
SPIRO[CYCLOBUTANE-1,3'-INDOLIN]-2'-ONE DERIVATIVES AS BROMODOMAIN INHIBITORS
-
Page/Page column 24, (2015/07/07)
The present invention provides novel spiro[cyclobutane-1,3'-indolin]-2'- derivatives of formula (I) in which Cy, R1, R2, L and 'm' are have the meaning given in the specification, and pharmaceutically acceptable salts thereof. The co
PHARMACEUTICAL COMPOUNDS
-
Page/Page column 23; 24, (2013/05/23)
Benzimidazoles of formula (I): wherein: A is 5-to 12-membered aryl or 5-to 12-membered heteroaryl, each of which is unsubstituted or substituted; Y is a single bond, -(CH2)p-, -X-, -CH2-X-, or -X-CH2-; X is -O-, -S-, -N(R2)-, >C=O, >S(=O), >S(=O)2, -O-C(=O)-, -C(=O)-O-, N(R2)-C(=O)-, or -C(=O)-N(R2)-; each L is independently a single bond, C1-3alkylene, C2-3alkenylene or C2-3alkynylene; R1is C1-6alkyl, C2-6alkenyl or C2-6alkynyl, each of which is unsubstituted or substituted; each Z is independently -N(R2)2, -OR2, -SR2, -S(=O)R2, -S(=O)2R2; each R2 is independently hydrogen, C1-6alkyl, C2-6alkenyl or C2-6 alkynyl, wherein said alkyl, alkenyl and alkynyl groups are unsubstituted or substituted; m is 0, 1, 2, or 3; n is 1, 2, or 3; and p is 1, 2, or 3; and the pharmaceutically acceptable salt thereof are inhibitors of RSV and can therefore be used to treat or prevent an RSV infection.
