1034927-02-0Relevant articles and documents
Diacid linkers that promote parallel β-sheet secondary structure in water
Freire, Felix,Fisk, John D.,Peoples, Aaron J.,Ivancic, Monika,Guzei, Ilia A.,Gellman, Samuel H.
supporting information; experimental part, p. 7839 - 7841 (2009/02/01)
We report the development of diacid units that promote formation of a two-stranded parallel β-sheet secondary structure between peptide segments attached via their N-termini. These linker units are formed by attaching glycine to one carboxyl group of cis-1,2-cyclohexanedicarboxylic acid (CHDA). Parallel sheet formation in water is observed when L-residue strands are attached to the CHDA-Gly unit with either of the two absolute configurations. Copyright