1035690-56-2

Basic information

• Product Name: 2-(3-(difluoroMethoxy)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
• Synonyms: 2-(3-(difluoroMethoxy)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
• CAS NO: 1035690-56-2
• Molecular Formula: C₁₃H₁₇BF₂O₃
• Molecular Weight: 270.0800864
• Mol File: 1035690-56-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 326.1±37.0 °C(Predicted)
• Appearance: /
• Density: 1.13±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 2-(3-(difluoroMethoxy)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-(difluoroMethoxy)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(1035690-56-2)
• EPA Substance Registry System: 2-(3-(difluoroMethoxy)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane(1035690-56-2)

Safety Data

• Hazardous Substances Data: 1035690-56-2(Hazardous Substances Data)

Usage

General Description

2-(3-(difluoroMethoxy)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane is a chemical compound that is commonly used in organic synthesis and medicinal chemistry. It is a boronic ester derivative with a difluoromethoxyphenyl and tetramethyl substituents. 2-(3-(difluoroMethoxy)phenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane is used as a reagent in organic reactions, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. It is also used in the development of pharmaceuticals and agrochemicals due to its ability to modify the activity of biological molecules. Additionally, it is known for its stability and compatibility with a wide range of functional groups, making it a versatile and valuable tool in chemical research and development.

Upstream product

• 591-20-8 3-Bromophenol 
• 73183-34-3 bis(pinacol)diborane 
• 262587-05-3 (3-bromophenyl)difluoromethyl ether 

Downstream Products

• 1142224-91-6 methyl 3'-((difluoromethyl)oxy)-2-(2,2-dimethylcyclopentyl)-1,1'-biphenyl-4-carboxylate 
• 1142224-93-8 (3'-((difluoromethyl)oxy)-2-(2,2-dimethylcyclopentyl)-1,1'-biphenyl-4-yl)methanol 
• 1142234-76-1 (3'-((difluoromethyl)oxy)-2-(2,2-dimethylcyclopentyl)-1,1'-biphenyl-4-yl)methanol 
• 1142234-74-9 (3'-((difluoromethyl)oxy)-2-(2,2-dimethylcyclopentyl)-1,1'-biphenyl-4-yl)methanol 
• 1354286-44-4 N-(5-(3-(difluoromethoxy)phenyl)-2-morpholinopyridin-4-yl)-5,7-difluoro-3-methyl-2-(pyridin-2-yl)quinolin-4-amine 
• 1252807-72-9 C₂₆H₂₁F₂NO₄ 
• 1252807-73-0 C₂₇H₂₃F₂NO₃ 
• 1252807-71-8 C₂₄H₁₉F₂NO₄S 
• 1252807-70-7 C₂₆H₂₀F₂N₂O₂ 

Relevant articles and documents

NOVEL THYROMIMETICS

Compounds are provided having the structure of Formula (I) or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein R1, R2, X1, X2, Y1, and Y2 are as defined herein. Such compounds function as thyromimetics and have utility for treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods of their use and preparation.

NOVEL THYROMIMETICS

Compounds are provided having the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein A, X1, X2, Q, R1, R2 and n are as defined herein. Such compounds function as thyromimetics and have utility for treating diseases such as neurodegenerative disorders and fibrotic diseases. Pharmaceutical compositions containing such compounds are also provided, as are methods of their use and preparation.

HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE

Disclosed are compounds having the formula (I): wherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.