1036764-25-6

Basic information

• Product Name: C₇₁H₁₁₈N₆O₁₁
• Synonyms: C₇₁H₁₁₈N₆O₁₁
• CAS NO: 1036764-25-6
• Molecular Weight: 1231.75
• Mol File: 1036764-25-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₇₁H₁₁₈N₆O₁₁(CAS DataBase Reference)
• NIST Chemistry Reference: C₇₁H₁₁₈N₆O₁₁(1036764-25-6)
• EPA Substance Registry System: C₇₁H₁₁₈N₆O₁₁(1036764-25-6)

Safety Data

• Hazardous Substances Data: 1036764-25-6(Hazardous Substances Data)

Upstream product

• 1036764-53-0 N-benzyl-N'-12-aminododecyl-4,13-diaza-18-crown-6 
• 19360-67-9 4-carboxymethoxy-benzoic acid 

Relevant articles and documents

Synthetic cation transporters incorporating crown ethers and calixarenes as headgroups and central relays: A comparison of sodium and chloride selectivity

An earlier study showed that a calix[4]arene could function as a central relay unit to form an ion conductance pathway through a phospholipid bilayer membrane. The present study expands the range of compounds from calix[4]arene to calix[6]arene and incorporates them either as central units or as headgroups, substituting one or more diaza-18-crown-6 residues in functioning hydraphiles. Ion release was assayed by detecting either Na+ or Cl- release from phospholipid vesicles. The ion transport activity for calix[4]arenes in either position is modest, but is almost non-existent when calix[6] residues were incorporated either as head groups or central relay units. The poor activity of the calix[6]arenes may result from an inability to penetrate to the midplane of the bilayer or pass entirely through it to form a conductance pathway. The transmembrane flip-flop may result from high polarity or steric bulk, or both. A hydraphile incorporating a single -NHCOC6H4OCH2CONH- as a central relay proved to be an excellent Na+ conductor, but less selective for Cl -. The fact that this new hydraphile molecule shows selectivity for Na+ over Cl- transport and possesses two secondary amide residues in the central relay suggests a means to control ion selectivity in synthetic ion transporters. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique.