1038916-08-3

Basic information

• Product Name: (S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylicacid
• Synonyms: (S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylicacid;2-{4-[(3S)-1-(tert-butoxycarbonyl)piperidin-3-yl]phenyl}-2H-indazole-7-carboxylic acid;EOS-60866
• CAS NO: 1038916-08-3
• Molecular Formula: C₂₄H₂₇N₃O₄
• Molecular Weight: 421.48888
• Mol File: 1038916-08-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylicacid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylicacid(1038916-08-3)
• EPA Substance Registry System: (S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylicacid(1038916-08-3)

Safety Data

• Hazardous Substances Data: 1038916-08-3(Hazardous Substances Data)

Usage

Description

(S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylic acid is a synthetic indazole derivative featuring a carboxylic acid group and a piperidine ring, with a tert-butoxycarbonyl group attached. (S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylicacid's structure indicates its potential pharmaceutical applications, possibly as an inhibitor or modulator of specific biological pathways or receptors. Its exact pharmaceutical potential and applications require further research to be determined.

Uses

Used in Pharmaceutical Industry:
(S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylic acid is used as a potential drug candidate for its possible role as an inhibitor or modulator of biological pathways or receptors. The presence of the tert-butoxycarbonyl group suggests its utility as a protective group in organic synthesis, which could be crucial in the development of new pharmaceuticals.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-2-(4-(1-(tert-butoxycarbonyl)piperidin-3-yl)phenyl)-2H-indazole-7-carboxylic acid is used as a protective group for functional groups during chemical reactions. This application is essential for preventing unwanted side reactions and ensuring the selective formation of desired products in complex synthetic sequences.

Upstream product

• 1476776-61-0 C₁₁H₁₃BrO₂ 
• 108-86-1 bromobenzene 
• 1476776-66-5 (S)-4-(4-bromophenyl)-5-((tert-butoxycarbonyl)amino)pentyl methanesulfonate 
• 1476776-64-3 (S)-tert-butyl (2-(4-bromophenyl)-5-hydroxypentyl)carbamate 
• 1476776-62-1 C₁₁H₁₆BrNO 
• 1335523-82-4 4-(3S-piperidine-3-yl)bromobenzene 
• 1476776-53-0 (S)-3-(4-bromophenyl)piperidin-1-ium 4-methylbenzenesulfonate 
• 1476776-44-9 (S)-5-(4-bromophenyl)piperidin-2-one 
• 1476776-40-5 isopropyl 4-(4-bromophenyl)-5-oxopentanoate 
• 1476776-39-2 isopropyl 3-(2-(4-bromophenyl)oxiran-2-yl)-propanoate 
• 1284448-67-4 isopropyl 4-(4-bromophenyl)-4-oxobutanoate 
• 6340-79-0 4-oxo-4-(4-bromophenyl)butanoic acid 
• 132874-06-7 methyl 3-(bromomethyl)-2-nitrobenzoate 
• 586-78-7 para-nitrophenyl bromide 

Downstream Products

• 1038916-11-8 tert-butyl (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate 
• 1038915-64-8 (3S)-3-[4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl]piperidinium chloride 

Relevant articles and documents

Derivative based on PARP inhibitor Niraparib and a preparation method and use thereof

The invention discloses a derivative based on a PARP inhibitor Niraparib. The derivative has a structure shown in a formula I as shown in the description, wherein R1 is selected from alkyl, alkoxy, cycloalkyl, aryl alkyl, cycloalkyl alkyl, heterocyclyl, a

Development of a fit-for-purpose large-scale synthesis of an oral PARP inhibitor

Compound (1) a poly(ADP-ribose)polymerase (PARP) inhibitor has been made by a fit-for-purpose large-scale synthesis using either a classical resolution or chiral chromatographic separation. The development and relative merits of each route are discussed,